Saltar al contenido
Merck

ATP1B1

ATPase, Na+/K+ transporting, beta 1 polypeptide

Sinónimos:
ATP1B
Especie:
ID UniProtKB:
ID del gen:
  • Human(481) Summary: The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known. [provided by RefSeq, Mar 2010]
  • Mouse(11931) ATPase, Na+/K+ transporting, beta 1 polypeptide
  • Rat(25650) ATPase, Na+/K+ transporting, beta 1 polypeptide
  • cow(519758) ATPase, Na+/K+ transporting, beta 1 polypeptide
  • Domestic Rabbit(100008749) ATPase, Na+/K+ transporting, beta 1 polypeptide
  • Horse(100033968) ATPase, Na+/K+ transporting, beta 1 polypeptide
  • naked mole-rat(101701102) ATPase, Na+/K+ transporting, beta 1 polypeptide
  • chicken(396529) ATPase, Na+/K+ transporting, beta 1 polypeptide
  • dog(403966) ATPase, Na+/K+ transporting, beta 1 polypeptide
  • domestic cat(101081858) ATPase, Na+/K+ transporting, beta 1 polypeptide
  • sheep(443384) ATPase, Na+/K+ transporting, beta 1 polypeptide
  • domestic guinea pig(100135483) ATPase, Na+/K+ transporting, beta 1 polypeptide

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-ATP1B1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-ATP1B1 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-ATP1B1, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
dog, horse, human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-ATP1B1 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-ATP1B1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
bovine, canine, human, mouse, pig, rat
Aplicación
ELISA
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Ouabain octahydrate, ≥95% (HPLC), powder,
Especie
rat, human
Digitoxin, ≥92% (HPLC), powder,
Especie
human
Digoxin, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Digitoxin, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Digoxin, analytical standard,
Especie
human

Proteins

Referencia del producto
Descripción
Especie
Adenosine 5′-Triphosphatase from porcine cerebral cortex, lyophilized powder, ≥0.3 units/mg protein, pH 7.8,
Especie

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Atp1b1,
Especie
mouse
MISSION® esiRNA, targeting human ATP1B1,
Especie
human