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Merck

ANTXR1

anthrax toxin receptor 1

Sinónimos:
ATR, GAPO, TEM8
Especie:
ID UniProtKB:
ID del gen:
  • Human(84168) Summary: This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]
  • Mouse(69538) anthrax toxin receptor 1
  • Rat(362393) anthrax toxin receptor 1
  • naked mole-rat(101701494) anthrax toxin receptor 1
  • domestic guinea pig(100728514) anthrax toxin receptor 1
  • sheep(101108204) anthrax toxin receptor 1
  • Domestic Rabbit(100357637) anthrax toxin receptor 1
  • cow(616010) anthrax toxin receptor 1
  • domestic cat(101092930) anthrax toxin receptor 1
  • Horse(100061334) anthrax toxin receptor 1
  • dog(612601) anthrax toxin receptor 1
  • chicken(428199) anthrax toxin receptor 1

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-ATR antibody produced in rabbit, purified antibody (Ion exchange),
Reactividad de especies
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-ATR antibody produced in rabbit, purified antibody (Ion exchange),
Reactividad de especies
Aplicación
immunofluorescence
western blot
Anti-ANTXR1 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicación
western blot

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human ANTXR1,
Especie
human
MISSION® esiRNA, targeting mouse Antxr1,
Especie
mouse