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Merck

ANK3

ankyrin 3, node of Ranvier (ankyrin G)

Sinónimos:
ANKYRIN-G
Especie:
ID UniProtKB:
ID del gen:
  • Human(288) Summary: Ankyrins are a family of proteins that are believed to link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact, and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 3 is an immunologically distinct gene product from ankyrins 1 and 2, and was originally found at the axonal initial segment and nodes of Ranvier of neurons in the central and peripheral nervous systems. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]
  • Mouse(11735) ankyrin 3, epithelial
  • Rat(361833) ankyrin 3, node of Ranvier (ankyrin G)
  • naked mole-rat(101719656) ankyrin 3, node of Ranvier (ankyrin G)
  • domestic guinea pig(100734552) ankyrin 3, node of Ranvier (ankyrin G)
  • sheep(101120296) ankyrin 3, node of Ranvier (ankyrin G)
  • chicken(396309) ankyrin 3, node of Ranvier (ankyrin G)
  • Horse(100062775) ankyrin 3, node of Ranvier (ankyrin G)
  • domestic cat(101097842) ankyrin 3, node of Ranvier (ankyrin G)
  • dog(479215) ankyrin 3, node of Ranvier (ankyrin G)
  • cow(511203) ankyrin 3, node of Ranvier (ankyrin G)

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anticuerpo anti-anquirina-G, clon N106/36, clone N106/36, from mouse,
Reactividad de especies
rat
Aplicación
immunohistochemistry
Anti-ANK3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot
Anti-Ankyrin-G Antibody, clone 1D11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
affinity binding assay
immunocytochemistry

immunofluorescence

immunohistochemistry

western blot
Monoclonal Anti-Ankyrin G antibody produced in mouse, clone S106-20, purified immunoglobulin,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
Anti-ANK3 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunohistochemistry

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Ank3,
Especie
mouse
MISSION® esiRNA, targeting human ANK3,
Especie
human