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Merck

ALOX5AP

arachidonate 5-lipoxygenase-activating protein

Sinónimos:
FLAP
Especie:
ID UniProtKB:
ID del gen:
  • Human(241) Summary: This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]
  • Mouse(11690) arachidonate 5-lipoxygenase activating protein
  • Rat(29624) arachidonate 5-lipoxygenase activating protein
  • Horse(100034178) arachidonate 5-lipoxygenase-activating protein
  • cow(613869) arachidonate 5-lipoxygenase-activating protein
  • dog(477323) arachidonate 5-lipoxygenase-activating protein
  • domestic guinea pig(100733727) arachidonate 5-lipoxygenase-activating protein
  • chicken(770904) arachidonate 5-lipoxygenase-activating protein
  • naked mole-rat(101704126) arachidonate 5-lipoxygenase-activating protein
  • domestic cat(101090316) arachidonate 5-lipoxygenase-activating protein
  • Zebrafish(337376) arachidonate 5-lipoxygenase-activating protein

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-ALOX5AP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-FLAP/ALOX5AP (Internal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
canine, human
Aplicación
ELISA
immunohistochemistry

western blot
Anti-ALOX5AP (center) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
immunohistochemistry

western blot
Anti-FLAP/ALOX5AP, C-Terminal antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
flow cytometry

immunofluorescence

immunohistochemistry

western blot
Anti-FLAP Antibody, clone 2S7Z0, Rabbit Monoclonal, ,
Reactividad de especies
human
Aplicación
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
BW B70C, >98% (HPLC), solid,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human ALOX5AP,
Especie
human
MISSION® esiRNA, targeting mouse Alox5ap,
Especie
mouse