- Direct amination of α-substituted nitroacetates using di-tert-butyl azodicarboxylate catalyzed by Hatakeyama's catalyst β-ICD.
Direct amination of α-substituted nitroacetates using di-tert-butyl azodicarboxylate catalyzed by Hatakeyama's catalyst β-ICD.
Organic & biomolecular chemistry (2012-01-11)
Cong-Bin Ji, Yun-Lin Liu, Xiao-Li Zhao, Yin-Long Guo, Hao-Yang Wang, Jian Zhou
PMID22231285
ABSTRACT
We report the first example of catalytic asymmetric direct amination of α-monosubstituted nitroacetates using di-tert-butyl azodicarboxylate. The simple and easily available Hatakeyama's catalyst β-ICD 11 was found to be a highly enantioselective catalyst for this reaction.
MATERIALS
Product Number
Brand
Product Description