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  • Associations between single-nucleotide polymorphism in the FNDC3A and autism spectrum disorder in a Korean population.

Associations between single-nucleotide polymorphism in the FNDC3A and autism spectrum disorder in a Korean population.

Psychiatry research (2013-05-04)
Myungja Ro, JungWon Park, Min Nam, Hee Jung Bang, Jae Won Yang, Kyung-Sik Choi, Su Kang Kim, Joo-Ho Chung, KyuBum Kwack
ABSTRACT

Autism spectrum disorder (ASD) is a neurodevelopmental syndrome associated with impairments of reciprocal communication and cognitive function. Associations between single-nucleotide polymorphisms (SNPs) and ASD were analysed by logistic regression. Polymorphisms in fibronectin type III domain-containing 3A (FNDC3A) exhibited significant associations in genotype and diplotype analyses. We conclude that FNDC3A influences the prevalence of ASD.