- Exonuclease-assisted cascaded recycling amplification for label-free detection of DNA.
Exonuclease-assisted cascaded recycling amplification for label-free detection of DNA.
Chemical communications (Cambridge, England) (2011-12-07)
Sai Bi, Li Li, Yangyang Cui
PMID22143422
ABSTRACT
The network consisting of three kinds of unlabeled stem-loop DNA molecular beacons (MBs) is activated by target DNA in the presence of exonuclease-III (Exo-III), achieving the concept of exonuclease-assisted cascaded recycling amplification (Exo-CRA) for DNA detection with a wide dynamic range of 8 orders of magnitude.