SML2592

Arteether

≥95% (HPLC)

• Synonym(s): β-Arteether, (+)-Arteether, (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-Ethoxydecahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, Dihydroartemisinin ethyl ether
• Empirical Formula (Hill Notation): C₁₇H₂₈O₅
• CAS Number: 75887-54-6
• Molecular Weight: 312.40
• MDL number: MFCD00869355
• UNSPSC Code: 51111800
• NACRES: NA.77

Properties

• Assay: ≥95% (HPLC)
• form: powder
• optical activity: [α]/D +148 to +165°, c = 1 in chloroform-d
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: −20°C
• InChI: 1S/C17H28O5/c1-5-18-14-11(3)13-7-6-10(2)12-8-9-16(4)20-15(19-14)17(12,13)22-21-16/h10-15H,5-9H2,1-4H3/t10-,11-,12+,13+,14+,15-,16?,17-/m1/s1
• InChI key: NLYNIRQVMRLPIQ-BVCZABNKSA-N

Description

Biochem/physiol Actions

Arteether is a semisynthetic artemisinin derivative with antimalarial activity. It has been used for the treatment of chloroquine-resistant Plasmodium falciparum malaria and cerebral malaria, and has also been shown to have anticancer activity.

Safety Information

• Pictograms: GHS08
• Signal Word: Warning
• Hazard Statements: H361d
• Precautionary Statements: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 2
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable