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Merck

PSMB3

proteasome (prosome, macropain) subunit, beta type, 3

Synonyms:
HC10-II
Species:
UniProtKB ID:
Gene ID:
  • Human(5691) Summary: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Pseudogenes have been identified on chromosomes 2 and 12. [provided by RefSeq, Jul 2008]
  • Mouse(26446) proteasome (prosome, macropain) subunit, beta type 3
  • Rat(29676) proteasome (prosome, macropain) subunit, beta type 3
  • chicken(419997) proteasome (prosome, macropain) subunit, beta type, 3
  • sheep(101120589) proteasome (prosome, macropain) subunit, beta type, 3
  • cow(533874) proteasome (prosome, macropain) subunit, beta type, 3
  • dog(480537) proteasome (prosome, macropain) subunit, beta type, 3
  • Zebrafish(573095) proteasome (prosome, macropain) subunit, beta type, 3
  • naked mole-rat(101720602) proteasome (prosome, macropain) subunit, beta type, 3
  • domestic cat(101087282) proteasome (prosome, macropain) subunit, beta type, 3
  • domestic guinea pig(100719768) proteasome (prosome, macropain) subunit, beta type, 3

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PSMB3 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-PSMB3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-PSMB3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Psmb3,
Species
mouse
MISSION® esiRNA, targeting human PSMB3,
Species
human