POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
Synonyms:
POLR2, POLRA, RPB1, RPBh1, RPO2, RPOL2, RpIILS, hRPB220, hsRPB1
Species:
Human POLR2A (5430), Mouse Polr2a (20020), Rat Polr2a (363633), cow POLR2A (282312), naked mole-rat Polr2a (101725588), dog POLR2A (479483), Zebrafish polr2a (553347), sheep POLR2A (100144762), domestic cat POLR2A (101098500), domestic guinea pig Polr2a (100734232)
UniProtKB ID:
Gene ID:
- Human(5430) Summary: This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008]
- Mouse(20020) polymerase (RNA) II (DNA directed) polypeptide A
- Rat(363633) polymerase (RNA) II (DNA directed) polypeptide A
- cow(282312) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
- naked mole-rat(101725588) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
- dog(479483) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
- Zebrafish(553347) polymerase (RNA) II (DNA directed) polypeptide A
- sheep(100144762) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
- domestic cat(101098500) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
- domestic guinea pig(100734232) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-POLR2A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-RNA Polymerase II Antibody, CTD Antibody, clone 8WG16, clone 8WG16, from mouse,
Species Reactivity
human, yeast
Application
dot blot
immunoprecipitation (IP)
inhibition assay
western blot
immunoprecipitation (IP)
inhibition assay
western blot
Anti-phospho RNA Pol II (Ser2), clone 3E7C7 Antibody, clone 3E7C7, from rat,
Species Reactivity
canine, human, monkey, mouse, rat
Application
ChIP
ELISA
immunocytochemistry
western blot
ELISA
immunocytochemistry
western blot
Anti-phospho RNA Pol II (Ser5), clone 1H4B6 Antibody, clone 1H4B6, from rat,
Species Reactivity
canine, human, monkey, mouse, rat
Application
ChIP
ELISA
immunocytochemistry
western blot
ELISA
immunocytochemistry
western blot
Goat anti-RNA Polymerase II Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Species Reactivity
human, mouse
Application
immunoprecipitation (IP)
western blot
western blot