Skip to Content
Merck

KDM2B

lysine (K)-specific demethylase 2B

Synonyms:
CXXC2, FBXL10, Fbl10, JHDM1B, PCCX2
Species:
UniProtKB ID:
Gene ID:
  • Human(84678) Summary: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(30841) lysine (K)-specific demethylase 2B
  • Rat(304495) lysine (K)-specific demethylase 2B
  • domestic guinea pig(100726076) lysine (K)-specific demethylase 2B
  • Horse(100059690) lysine (K)-specific demethylase 2B
  • domestic cat(101094455) lysine (K)-specific demethylase 2B
  • cow(614487) lysine (K)-specific demethylase 2B
  • naked mole-rat(101696346) lysine (K)-specific demethylase 2B
  • sheep(101103759) lysine (K)-specific demethylase 2B
  • chicken(416844) lysine (K)-specific demethylase 2B
  • dog(486262) lysine (K)-specific demethylase 2B

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-JHDM1B Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
chimpanzee, horse, human, mouse, porcine, rabbit, rat
Application
immunocytochemistry
western blot
ChIPAb+ JHDM1B Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
chimpanzee, equine, horse, human, mouse, pig, porcine, rabbit, rat
Application
ChIP
dot blot

western blot
Anti-KDM2B/FBXL10 Antibody, clone 2F12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, canine, feline, goat, human, monkey, mouse, rat
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot

Proteins

Product Number
Description
Species
FBXL10 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human KDM2B,
Species
human