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Merck

FBXL7

F-box and leucine-rich repeat protein 7

Synonyms:
FBL6, FBL7
Species:
UniProtKB ID:
Gene ID:
  • Human(23194) Summary: This gene encodes a member of the F-box protein family which is characterized by a 42-48 amino acid motif, the F-box, which binds to the S-phase kinase-associated protein 1 (Skp1) protein. The F-box proteins constitute one of the four subunits of E3 ubiquitin protein ligases called SCFs (SKP1-Cul1-F-box), which play a role in phosphorylation-dependent ubiquitination of proteins. The F-box proteins are divided into 3 subfamilies based on the other domain in the protein: F-box proteins that also have a WD-40 domain (Fbws subfamily), F-box proteins that also have leucine-rich repeats (Fbls subfamily) and F-box proteins that contain other motifs or lack known protein-interaction domains (Fbxs subfamily). The protein encoded by this gene belongs to the Fbls subfamily. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
  • Mouse(448987) F-box and leucine-rich repeat protein 7
  • Rat(361907) F-box and leucine-rich repeat protein 7
  • domestic guinea pig(100720048) F-box and leucine-rich repeat protein 7
  • cow(518806) F-box and leucine-rich repeat protein 7
  • Horse(100070113) F-box and leucine-rich repeat protein 7
  • domestic cat(101089921) F-box and leucine-rich repeat protein 7
  • chicken(428492) F-box and leucine-rich repeat protein 7
  • dog(489262) F-box and leucine-rich repeat protein 7
  • sheep(101102932) F-box and leucine-rich repeat protein 7
  • naked mole-rat(101700886) F-box and leucine-rich repeat protein 7

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-FBXL7 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
guinea pig, human, mouse, rat
Application
immunohistochemistry
western blot
Monoclonal Anti-FBXL7 antibody produced in mouse, clone 2G10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-FBXL7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Fbxl7,
Species
mouse
MISSION® esiRNA, targeting human FBXL7,
Species
human