CYP11A1
cytochrome P450, family 11, subfamily A, polypeptide 1
Synonyms:
CYP11A, CYPXIA1, P450SCC
Species:
Human CYP11A1 (1583), Mouse Cyp11a1 (13070), Rat Cyp11a1 (29680), sheep CYP11A1 (100048994), Domestic Rabbit CYP11A1 (100345737), cow CYP11A1 (338048), Zebrafish cyp11a1 (80374), chicken CYP11A1 (414838), Horse CYP11A1 (100034229), dog CYP11A1 (478365)
UniProtKB ID:
Gene ID:
- Human(1583) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq, Jul 2008]
- Mouse(13070) cytochrome P450, family 11, subfamily a, polypeptide 1
- Rat(29680) cytochrome P450, family 11, subfamily a, polypeptide 1
- sheep(100048994) cytochrome P450, family 11, subfamily A, polypeptide 1
- Domestic Rabbit(100345737) cytochrome P450, family 11, subfamily A, polypeptide 1
- cow(338048) cytochrome P450, family 11, subfamily A, polypeptide 1
- Zebrafish(80374) cytochrome P450, subfamily XIA, polypeptide 1
- chicken(414838) cytochrome P450, family 11, subfamily A, polypeptide 1
- Horse(100034229) cytochrome P450 cholesterol side-chain cleavage
- dog(478365) cytochrome P450, family 11, subfamily A, polypeptide 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CYP11A1 Antibody, clone 2M5 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
chimpanzee, human
Application
affinity binding assay
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-CYP11A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-CYP11A1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-Cytochrome P450 (scc) Antibody, a.a. 509-526, from rabbit, purified by affinity chromatography,
Species Reactivity
rat
Application
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,
Species
human