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Merck

BMPR1A

bone morphogenetic protein receptor, type IA

Synonyms:
10q23del, ACVRLK3, ALK3, CD292, SKR5
Species:
UniProtKB ID:
Gene ID:
  • Human(657) Summary: The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq, Jul 2008]
  • Mouse(12166) bone morphogenetic protein receptor, type 1A
  • Rat(81507) bone morphogenetic protein receptor, type IA
  • Goat(100861241) bone morphogenetic protein receptor, type IA
  • Domestic Rabbit(100350518) bone morphogenetic protein receptor, type IA
  • sheep(101112282) bone morphogenetic protein receptor, type IA
  • dog(489077) bone morphogenetic protein receptor, type IA
  • cow(404101) bone morphogenetic protein receptor, type IA
  • domestic cat(101089548) bone morphogenetic protein receptor, type IA
  • naked mole-rat(101700899) bone morphogenetic protein receptor, type IA
  • chicken(396308) bone morphogenetic protein receptor, type IA
  • Horse(100064367) bone morphogenetic protein receptor, type IA
  • domestic guinea pig(100723350) bone morphogenetic protein receptor, type IA

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ELISA

Product Number
Description
Species
Human BMPR-IA ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-BMPR-1A, clone 4B7B2 Antibody, ascites fluid, clone 4B7B2, from mouse,
Species Reactivity
human, mouse
Application
ELISA
flow cytometry

immunohistochemistry

western blot
Anti-BMPR1A antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human
Application
ELISA
western blot
Anti-BMPR-1A Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse, rat
Application
western blot

Proteins

Product Number
Description
Species
ALK3 (187-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Bmpr1a,
Species
mouse
MISSION® esiRNA, targeting human BMPR1A,
Species
human