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Merck

ADRA1A

adrenoceptor alpha 1A

Synonyms:
ADRA1C, ADRA1L1, ALPHA1AAR
Species:
UniProtKB ID:
Gene ID:
  • Human(148) Summary: Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq, Jul 2008]
  • Mouse(11549) adrenergic receptor, alpha 1a
  • Rat(29412) adrenoceptor alpha 1A
  • cow(282134) adrenergic, alpha-1A-, receptor
  • domestic cat(101098375) adrenoceptor alpha 1A
  • domestic guinea pig(100135474) adrenergic receptor, alpha 1a
  • dog(403866) adrenoceptor alpha 1A
  • sheep(100169940) adrenoceptor alpha 1A
  • chicken(428203) adrenoceptor alpha 1A
  • naked mole-rat(101712485) adrenoceptor alpha 1A
  • Domestic Rabbit(100009237) adrenoceptor alpha 1A

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  • Custom Gene Products

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Small Molecule - Agonist

Product Number
Description
Species
Phenylephrine hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Species
human
Alfuzosin hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Species
human
Alfuzosin hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
3-[(1R)-1-Hydroxy-2-(methylamino)ethyl]phenol, AldrichCPR,
Species
human
Phenylephrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
Dapiprazole hydrochloride, ≥98% (HPLC),
Species
human
Eliprodil, ≥98% (HPLC), powder,
Species
human, rat
Terazosin hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Species
human
Naftopidil hydrochloride hydrate, solid,
Species
human
Benoxathian hydrochloride, solid,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ADRA1A antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
Monoclonal Anti-ADRA1A, (N-terminal) antibody produced in mouse, clone 5G8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-ADRA1A antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
western blot
Anti-ADRA1A Antibody, clone 4G10W8, Rabbit Monoclonal, ,
Species Reactivity
mouse
Application
western blot
Anti-ADRA1A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot

Proteins

Product Number
Description
Species
ChemiScreen Recombinant HumanMembrane Preparation

α1A Adrenergic Receptor
, Human alpha1A GPCR membrane preparation for Radioligand binding Assays & GTPγS binding.,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ADRA1A,
Species
human
MISSION® esiRNA, targeting human ADRA1A (2),
Species
human
MISSION® esiRNA, targeting mouse Adra1a,
Species
mouse