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32142

Supelco

Pirbuterol acetate

VETRANAL®, analytical standard

Synonym(s):

(RS)-2-(tert-Butylamino)-1-(6-hydroxymethyl-5-hydroxy-2-pyridyl)ethanol acetate salt, 6-(2-tert-Butylamino-1-hydroxyethyl)-2-hydroxymethylpyridin-3-ol acetate

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About This Item

Empirical Formula (Hill Notation):
C12H20N2O3 · C2H4O2
CAS Number:
Molecular Weight:
300.35
Beilstein:
13318829
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

InChI

1S/C12H20N2O3.C2H4O2/c1-12(2,3)13-6-11(17)8-4-5-10(16)9(7-15)14-8;1-2(3)4/h4-5,11,13,15-17H,6-7H2,1-3H3;1H3,(H,3,4)

InChI key

QSXMZJGGEWYVCN-UHFFFAOYSA-N

Gene Information

human ... ADRB2(154)

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


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Life-threatening asthma during treatment with salmeterol.
Miles Weinberger et al.
The New England journal of medicine, 355(8), 852-853 (2006-08-25)
Paradoxical asthma hazard of short-acting beta2-agonists.
M J Seed et al.
Allergy, 63(2), 241-241 (2007-11-22)
J S Kelloway et al.
Managed care interface, 10(9), 99-107 (1997-08-05)
Managed care plans evaluate therapeutic alternatives to identify the most cost-effective medications for asthma. Three hundred one patients with asthma were randomized to receive the beta-agonist pirbuterol from either a manually operated metered dose inhaler (MDI) or a breath-actuated inhaler
R Silverman et al.
Chest, 114(3), 766-770 (1998-09-22)
Patients with acute asthma often have difficulty using a conventional metered-dose inhaler. The Maxair Autohaler (3M Pharmaceuticals; St. Paul, MN) is a hand-held breath-actuated device developed to help patients coordinate drug administration. The study objective is to compare the efficacy
A E Carie et al.
Oncogene, 26(26), 3777-3788 (2007-01-30)
A chemical biology approach identifies a beta 2 adrenergic receptor (beta2AR) agonist ARA-211 (Pirbuterol), which causes apoptosis and human tumor regression in animal models. beta2AR stimulation of cAMP formation and protein kinase A (PKA) activation leads to Raf-1 (but not

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