AB5042
Anti-Choline Acetyltransferase Antibody
serum, Chemicon®
Synonym(s):
ChAT
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
guinea pig, rat, avian
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
chicken ... Chat(395314)
rat ... Chat(290567)
Specificity
Will stain cholinergic neurons in rat central and peripheral nervous systems.
Immunogen
A 22 amino acid synthetic peptide from porcine ChAT, coupled to KLH. The peptide sequence is GLFSSYRLPGHTQDTLVAQKSS. Due to sequence similarity, the antibody is expected to react with pig, rat, mouse and human ChAT.
Application
Detect Choline Acetyltransferase using this Anti-Choline Acetyltransferase Antibody validated for use in IH.
Immunohistochemistry: 1:2,000-1:4,000 in rat basal forebrain.
Western blot
Optimal working dilutions must be determined by the end user.
Western blot
Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Neuronal & Glial Markers
Neurotransmitters & Receptors
Neuronal & Glial Markers
Physical form
Lyophilized. Reconstitute with 100 μL of sterile distilled water. Contains no preservative.
Storage and Stability
Maintain lyophilized material dry at -20°C or -70°C for up to 6 months after date of receipt. After reconstitution, maintain at -20°C in undiluted aliquots for up to 6 months. Glycerol (1:1) can be added for additional stability.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Ying Li et al.
Anatomical record (Hoboken, N.J. : 2007), 294(5), 847-857 (2011-03-19)
Amyotrophic lateral sclerosis (ALS) is a progressively fatal, incurable, neurodegenerative disorder. In this study, we investigated whether olfactory ensheathing cells (OEC) transplantation could provide protection to motor neurons and enable remyelination in mutant SOD1(G93A) transgenic rats with ALS. Seventy-two rats
West Nile virus-induced acute flaccid paralysis is prevented by monoclonal antibody treatment when administered after infection of spinal cord neurons.
Morrey, JD; Siddharthan, V; Wang, H; Hall, JO; Skirpstunas, RT; Olsen, AL; Nordstrom et al.
Journal of Neurovirology null
Steffen Wolter et al.
Frontiers in neural circuits, 12, 65-65 (2018-10-03)
Sensory axon T-like branching (bifurcation) in neurons from dorsal root ganglia and cranial sensory ganglia depends on the molecular signaling cascade involving the secreted factor C-type natriuretic peptide, the natriuretic peptide receptor guanylyl cyclase B (GC-B; also known as Npr2)
Neurotransmitter synthesis in poststroke cortical neurogenesis in adult rats.
Gu, W; Gu, C; Jiang, W; Wester, P
Stem Cell Research null
Longhong Zhu et al.
Cellular and molecular life sciences : CMLS, 81(1), 16-16 (2024-01-09)
The nuclear loss and cytoplasmic accumulation of TDP-43 (TAR DNA/RNA binding protein 43) are pathological hallmarks of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). Previously, we reported that the primate-specific cleavage of TDP-43 accounts for its cytoplasmic mislocalization
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