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Key Documents

AB10428

Sigma-Aldrich

Anti-Kallikrein-3 (KLK3) (CT) Antibody

from rabbit

Synonym(s):

P-30 antigen, Kallikrein-3, kallikrein-related peptidase 3

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

saturated ammonium sulfate (SAS) precipitated

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, rat, human

technique(s)

western blot: suitable

NCBI accession no.

NP_001639

UniProt accession no.

P07288

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... KLK3(354)

General description

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK3 is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein.

Specificity

Other species have not been tested.
The antibody reacts with the 29 kDa KLK3 antigen.

Immunogen

This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human KLK3.

Application

This Anti-Kallikrein-3 (KLK3) (C-term) Antibody is validated for use in WB for the detection of Kallikrein-3 (KLK3) (C-term).

Quality

Western Blot Analysis: 1:250 dilution of this antibody detected KLK3 on mouse brain lysate.

Target description

~31 kDa observed.
Band may migrate from the calculated 29 kDa to ~31 kDa on western blot.

Physical form

Format: Purified
Saturated Ammonium Sulfate (SAS)

Storage and Stability

Store at 2-8°C for 6 months from date of receipt. For long term storage, store at -20°

Analysis Note

Control
Western Blot : Mouse brain lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ana M Blázquez-Medela et al.
Medicine, 94(41), e1617-e1617 (2015-10-16)
Early detection of hypertensive end-organ damage and secondary diseases are key determinants of cardiovascular prognosis in patients suffering from arterial hypertension. Presently, there are no biomarkers for the detection of hypertensive target organ damage, most outstandingly including blood vessels, the

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