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Key Documents

SML3903

Sigma-Aldrich

Insulin glargine

≥95% (HPLC)

Synonym(s):

HOE 901, [GlyA21,ArgB31,ArgB32]insulin

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About This Item

Empirical Formula (Hill Notation):
C267H404N72O78S6
CAS Number:
Molecular Weight:
6062.89
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

Assay

≥95% (HPLC)

form

(Powder or Lyophilized powder or film)

storage condition

desiccated

color

white to off-white

storage temp.

-10 to -25°C

Biochem/physiol Actions

Insulin glargine is an approved long-acting insulin analog used for management of Diabetes Type 1 and Type 2. Insulin glargine is a human insulin analog where A-chain asparagine 21 was replaced by glycine and B-chain carboxy terminal was extended by two arginine residues.

Caution

Hygroscopic

Storage Class Code

11 - Combustible Solids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Twenty Years of Insulin Gla-100: A Systematic Evaluation of Its Efficacy and Safety in Type 2 Diabetes Mellitus
Diabetes therapy : research, treatment and education of diabetes and related disorders, 13(8), 1409-1481 (2022)
Insulin glargine: a systematic review of a long-acting insulin analogue
Clinical Therapeutics, 25(6), 1541-1577 (2003)
Growth promoting and metabolic activity of the human insulin analogue [GlyA21,ArgB31,ArgB32]insulin (HOE 901) in muscle cells
European Journal of Pharmacology, 320(2-3), 259-265 (1997)

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