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Eprinomectin

PESTANAL®, analytical standard, mixture of isomers

Synonym(s):

(4′’R)-4″-(Acetylamino)-4″-deoxy-avermectin B1

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About This Item

Empirical Formula (Hill Notation):
C50H75NO14
CAS Number:
Molecular Weight:
914.13
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

PESTANAL®

quality

mixture of isomers

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

storage temp.

−20°C

SMILES string

C[C@H]1[C@H](NC(C)=O)[C@@H](OC)C[C@H](O[C@H]2[C@H](C)O[C@@H](O[C@H](/C(C)=C/C[C@]3([H])C[C@H]4C[C@@]5(O[C@@]([R])([H])[C@@H](C)C=C5)O3)[C@@H](C)/C=C/C=C(CO6)/[C@@]([C@@]6([H])[C@H](O)C(C)=C7)(O)[C@]7([H])C(O4)=O)C[C@@H]2OC)O1.CCC.CCCC

InChI

1S/C49H73NO14/c1-25(2)43-28(5)17-18-48(64-43)23-35-20-34(63-48)16-15-27(4)44(26(3)13-12-14-33-24-57-46-42(52)29(6)19-36(47(53)60-35)49(33,46)54)61-40-22-38(56-11)45(31(8)59-40)62-39-21-37(55-10)41(30(7)58-39)50-32(9)51/h12-15,17-19,25-26,28,30-31,34-46,52,54H,16,20-24H2,1-11H3,(H,50,51)/b13-12-,27-15-,33-14-/t26-,28-,30-,31-,34+,35-,36-,37+,38-,39-,40-,41+,42+,43+,44-,45+,46+,48+,49+/m0/s1

InChI key

WPNHOHPRXXCPRA-TVXIRPTOSA-N

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General description

Eprinomectin is a second generation macrocyclic lactone, used as a topical endectocide which is active both against endoparasites and ectoparasites for all cattle, including lactating dairy cows.

Application

Eprinomectin has been used as a standard for the determination of pesticide residues in soil samples by the on-line solid-phase extraction-ultra high performance liquid chromatography-tandem mass spectrometry. It may also be used to examine the presence of any veterinary drug residues in the bulk milk tank.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Eprinomectin: a novel avermectin for use as a topical endectocide for cattle.
Shoop W L, et al.
International Journal For Parasitology, 26(11), 1237-1242 (1996)
A B Forbes
Veterinary parasitology, 192(4), 308-312 (2013-01-01)
An extended-release injection, which is administered at a rate of 1 mg eprinomectin/kg body weight, has been developed to provide up to 150 days control of parasites of cattle. The product can facilitate the achievement of two of the fundamental
Steffen Rehbein et al.
Parasitology research, 111(3), 1343-1347 (2012-05-29)
A study was conducted to confirm the efficacy of topical eprinomectin against nematodes and to evaluate the pharmacokinetics in cattle prevented from having physical contact with other cattle and from self-grooming. Sixteen male Brown Swiss calves were infected with larvae
H W Ploeger et al.
Veterinary parasitology, 185(2-4), 335-338 (2011-11-15)
On two dairy farms it was attempted to eradicate lungworm, Dictyocaulus viviparus, by means of a single mass-treatment of all cattle that had been grazed the previous year(s), before turnout in the spring. Both farms experienced two years of lungworm
Huiqiang Wen et al.
Parasitology research, 106(3), 607-613 (2010-01-14)
Ear mange mite Psoroptes cuniculi, one of the predominant parasites in rabbits, can cause considerable weight loss, low favorable fee conversion rates, and meningitis. The present experiment was to investigate the difference of plasma disposition and the variation of clinical

Protocols

Test your food for fipronil contamination using our analytical standards, certified reference materials, solvents, and columns for analysis.

Test your food for fipronil contamination using our analytical standards, certified reference materials, solvents, and columns for analysis.

Test your food for fipronil contamination using our analytical standards, certified reference materials, solvents, and columns for analysis.

Test your food for fipronil contamination using our analytical standards, certified reference materials, solvents, and columns for analysis.

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