850993

2-Aminoisobutyric acid

98%, for peptide synthesis

• Synonym(s): α-Aminoisobutyric acid, 2-Methylalanine, Aib
• Linear Formula: (CH₃)₂C(NH₂)COOH
• CAS Number: 62-57-7
• Molecular Weight: 103.12
• Beilstein: 506496
• EC Number: 200-544-0
• MDL number: MFCD00008049
• UNSPSC Code: 12352106
• PubChem Substance ID: 24888304
• NACRES: NA.22

Properties

• product name: 2-Aminoisobutyric acid, 98%
• Assay: 98%
• form: solid
• reaction suitability: reaction type: solution phase peptide synthesis
• mp: ≥300 °C
• application(s): peptide synthesis
• SMILES string: CC(C)(N)C(O)=O
• InChI: 1S/C4H9NO2/c1-4(2,5)3(6)7/h5H2,1-2H3,(H,6,7)
• InChI key: FUOOLUPWFVMBKG-UHFFFAOYSA-N

Description

General description

2-Aminoisobutyric acid also known as α-aminobutyric acid, is an amino acid used in solution-phase peptide synthesis. It is a desirable building block for peptides because of its strong tendency to cause the peptide to form a helical shape.

Application

2-Aminoisobutyric acid can be used to synthesize self-assembled polypeptide nanoparticles. Incorporation of this compound into the peptide chain can prevent undesired reactions since it is di-α-substituted, and inert to C−H abstraction.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H319
• Precautionary Statements: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves