135615

2-Bromo-2-methylpropane

98%

• Synonym(s): 2-methyl-2-bromopropane, tert-Butyl bromide
• Linear Formula: (CH₃)₃CBr
• CAS Number: 507-19-7
• Molecular Weight: 137.02
• Beilstein: 1730892
• EC Number: 208-065-9
• MDL number: MFCD00000125
• UNSPSC Code: 12352100
• PubChem Substance ID: 24848212
• NACRES: NA.22

Properties

• Assay: 98%
• form: liquid
• contains: 0.5% potassium carbonate as stabilizer
• refractive index: n20/D 1.4279 (lit.)
• bp: 71-73 °C (lit.)
• mp: −20 °C (lit.)
• solubility: H₂O: insoluble; organic solvents: miscible
• density: 1.22 g/mL at 20 °C (lit.)
• SMILES string: CC(C)(C)Br
• InChI: 1S/C4H9Br/c1-4(2,3)5/h1-3H3
• InChI key: RKSOPLXZQNSWAS-UHFFFAOYSA-N

Description

General description

2-Bromo-2-methylpropane (tert-Butyl bromide) is a versatile reactant in organic synthesis, facilitating the introduction of the tert-butyl group. It causes the massive deguanylation of guanine based-nucleosides and massive deadenylation of adenine based-nucleosides.

Application

2-Bromo-2-methylpropane was used to study the massive deadenylation of adenine based-nucleosides induced by halogenated alkanes under physiological conditions.

Safety Information

• Pictograms: GHS02
• Signal Word: Danger
• Hazard Statements: H225
• Precautionary Statements: P210 - P233 - P240 - P241 - P242 - P243
• Hazard Classifications: Flam. Liq. 2
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 60.8 °F - closed cup
• Flash Point(C): 16 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves