SAB5702145

Anti-HNF3β/FOXA2 Antibody, clone 9O4M2, Rabbit Monoclonal

• Sinónimos: FOXA2,HNF3B,TCF3B
• UNSPSC Code: 12352203
• NACRES: NA.46

Propiedades

• biological source: rabbit
• Quality Level: 100
• material: colorless
• clone: 9O4M2, monoclonal
• form: liquid
• mol wt: 52 kDa
• species reactivity: human, rat
• concentration: 2 mg/mL
• technique(s): immunofluorescence: 1:50 - 1:200; immunoprecipitation (IP): 1:50 - 1:200; western blot: 1:500 - 1:2000
• color: colorless
• isotype: IgG
• immunogen sequence: MLGAVKMEGHEPSDWSSYYAEPEGYSSVSNMNAGLGMNGMNTYMSMSAAAMGSGSGNMSAGSMNMSSYVGAGMSPSLAGMSPGAGAMAGMGGSAGAAGVA
• UniProt accession no.: Q9Y261
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... Foxa2(3170)

Descripción

General description

This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HNF3β/FOXA2 (Q9Y261).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IF/ICC, IP

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1