SAB5700663

Anti-MyD88 antibody produced in rabbit

• Sinónimos: MYD88, MYD88D, MyD88, myeloid differentiation primary response 88
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 15; 20; 28; 31; 33; 34
• species reactivity: rat, human, mouse
• concentration: 1.89 mg/ml
• technique(s): immunofluorescence: 1:50-1:200; western blot: 1:500-1:2000
• UniProt accession no.: Q99836
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... MYD88(4615)

Descripción

General description

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 60-309 of human MyD88 (NP_002459.2).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Información de seguridad

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable