SAB4200709

Anti-Collagen Type IV antibody, Mouse monoclonal

clone col-94, purified from hybridoma cell culture

• Sinónimos: Anti-col4a1/col4a2
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• forma del anticuerpo: purified from hybridoma cell culture
• Nivel de calidad: 200
• tipo de anticuerpo: primary antibodies
• clon: col-94, monoclonal
• Formulario: buffered aqueous solution
• reactividad de especies: monkey, human
• concentración: ~1 mg/mL
• técnicas: dot blot: suitable; electron microscopy: suitable; immunohistochemistry: 4-8 μg/mL using formalin-fixed, paraffin-embedded human tongue sections
• isotipo: IgG1
• Nº de acceso UniProt: P02462
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... COL4A1(1282)

Descripción

Descripción general

Anti-Collagen Type IV antibody, Mouse monoclonal (mouse IgG1 isotype) is derived from the col-94 hybridoma, produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mouse immunized with human collagen Type IV. Collagen Type IV (also known as COL4A) is a key component of the basement membranes (BM), which is found at the basal surface of epithelial and endothelial cells and is essential for tissue strength and polarity. Type IV Collagens are encoded by three pairs of paralogous genes (COL4A1 through COL4A6).

Inmunógeno

human collagen Type IV

Aplicación

Anti-Collagen Type IV antibody, Mouse monoclonal has been used in immunohistochemistry and dot-blotting.

Acciones bioquímicas o fisiológicas

Collagen Type IV represents a physical barrier against cell invasion. Proteolysis/degradation of Collagen Type IV is essential for cell migration and cancer cells invasion through the ECM into the interstitial tissues.

Forma física

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable