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N5413

Sigma-Aldrich

Anti-Nestin antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

Sinónimos:

Anti-FJ21841, Anti-NES, Anti-Nbla00170

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About This Item

MDL number:
MFCD03455626
UNSPSC Code:
12352203
NACRES:
NA.41
En este momento no podemos mostrarle ni los precios ni la disponibilidad

biological source

rabbit

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~110 kDa (cleaved)
antigen ~177 kDa
antigen ~270 kDa

species reactivity

rat, mouse, human

concentration

~1 mg/mL

technique(s)

flow cytometry: 1:200-1:500
immunohistochemistry: 1:100-1:200
western blot: 1:500-1:1,000

UniProt accession no.

P48681

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... NES(10763)
mouse ... Nes(18008)
rat ... Nes(25491)

General description

Nestin (NES) is a class VI cytoplasmic protein. It is expressed in the intermediate filaments and has a molecular weight of 177kDa. The gene encoding it is localized on human chromosome 1q23.1 with four exons.

Immunogen

synthetic peptide corresponding to residues 254-270 of human Nestin. This sequence is 93% identical in rat.

Biochem/physiol Actions

Nestin (NES) functions as a regulator of proteins which are involved in cell growth. It also interacts with other proteins of the intermediate filament. NES has been studied as a marker of neural stem cells.

Physical form

solution in phosphate buffered saline, containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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Certificados de análisis (COA)

Lot/Batch Number
SLCM8908
SLCK2368
SLCG0413
SLCC3419
SLBX5698

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International journal of nephrology and renovascular disease, 10, 61-76 (2017-03-07)
Several renal disorders affect the glomerular podocytes. Compensatory structural and functional changes have been observed in animals that have undergone unilateral renal ablation. These changes occur as a pliant response to quench the increased functional demand to maintain homeostasis of
Y Chen et al.
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Osteoarthritis (OA) is a progressive joint disorder. To date, there is not effective medical therapy. Joint distraction has given us hope for slowing down the OA progression. In this study, we investigated the benefits of joint distraction in OA rat
Nianping Zhang et al.
International journal of molecular medicine, 40(3), 814-824 (2017-07-18)
Pluripotent stem cells (PSCs) are regarded as potential sources that provide specific neural cells for cell therapy in some nervous system diseases. However, the mechanisms underlying the neural differentiation of PSCs remain largely unknown. MicroRNAs (miRNAs or miRs) are a class of
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