FLAAS

Adenosine 5′-triphosphate (ATP) disodium salt hydrate

vial of ~1 mg ATP

• Sinónimos: ATP disodium hydrate
• Fórmula lineal: C₁₀H₁₄N₅O₁₃P₃Na₂ · xH₂O
• Número de CAS: 34369-07-8
• Peso molecular: 551.14 (anhydrous basis)
• Número CE: 213-579-1
• Número MDL: MFCD00150755
• Código UNSPSC: 12352202
• eCl@ss: 32160414
• ID de la sustancia en PubChem: 24895005
• NACRES: NA.26

Propiedades

• origen biológico: bacterial (Corynebacterium sp)
• Nivel de calidad: 200
• Ensayo: ≥90%
• Formulario: lyophilized powder
• envase: vial of ~1 mg ATP
• temp. de almacenamiento: −20°C
• cadena SMILES: Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O
• InChI: 1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1
• Clave InChI: NTBQNWBHIXNPRU-MSQVLRTGSA-L

Descripción

Aplicación

Adenosine 5′-triphosphate (ATP) disodium salt hydrate has been:

• used as a standard to measure ATP by bioluminescence method[1]
• used in kinase buffer to assess the interaction between death-associated protein kinases (DAPK2) and 14-3-3-β[2]
• used as a standard in ATP colorimetric assay[3]

Acciones bioquímicas o fisiológicas

Adenosine 5′-triphosphate (ATP) is one of the nucleoside triphosphate present in living system. It controls various biologic processes such as glucose metabolism, muscle contraction and neurotransmission. Apart from this, ATP serves as an important energy source for the cell. Administration of ATP might be useful in the treatment of non-small-cell lung cancer.[4]

Adenosine 5′-triphosphate was shown to have inhibitory effects on the inflammatory response by abrogating secretion of TNF-α and promoting secretion of Interleukin-10. [5]

P₂ purinergic agonist; increases activity of Ca²⁺-activated K⁺ channels; substrate for ATP-dependent enzyme systems

Cantidad

Each vial contains ~1.2 mg of Na₂ATP • 3H₂O equivalent to ~1.0 mg of ATP (2.0 μmol). Actual amount printed on the label.

Nota de preparación

Prepared to be substantially vanadium-free.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)