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Documentos

P1240000

Phenylephrine

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

L-Phenylephrine

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About This Item

Fórmula empírica (notación de Hill):
C9H13NO2
Número de CAS:
59-42-7
Peso molecular:
167.21
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

phenylephrine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/t9-/m0/s1

InChI key

SONNWYBIRXJNDC-VIFPVBQESA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Phenylephrine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Referencia del producto
Descripción
Precios

PHR1017

Phenylephrine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

Y0000683

Phenylephrine hydrochloride for peak identification, European Pharmacopoeia (EP) Reference Standard

P1250000

Phenylephrine hydrochloride, European Pharmacopoeia (EP) Reference Standard

1533002

Phenylephrine hydrochloride, United States Pharmacopeia (USP) Reference Standard

PHR1695

Phenylephrine Related Compound C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1712

Phenylephrine Related Compound E, Pharmaceutical Secondary Standard; Certified Reference Material

1533046

Phenylephrine Related Compound E, United States Pharmacopeia (USP) Reference Standard

1533035

Phenylephrine Related Compound D, United States Pharmacopeia (USP) Reference Standard

1532950

Phenylephrine bitartrate, United States Pharmacopeia (USP) Reference Standard

1533024

Phenylephrine Related Compound C, United States Pharmacopeia (USP) Reference Standard

1533261

Phenylephrine Related Compound F, United States Pharmacopeia (USP) Reference Standard

1533272

Phenylephrine Related Compound G, United States Pharmacopeia (USP) Reference Standard

BP284

Phenylephrine hydrochloride, British Pharmacopoeia (BP) Reference Standard

PHR2153

2-Hydroxy-N-[(2R)-2-hydroxy-2-(3-hydroxyphenyl)ethyl]-N-methylacetamide, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2151

1,2,3,4-Tetrahydro-4,6-dihydroxy-2-methylisoquinoline hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2148

Phenylephrine Related Compound D, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2154

N-Formylphenylephrine, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2149

Phenylephrine Related Compound F, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2150

Phenylephrine Related Compound G, Pharmaceutical Secondary Standard; Certified Reference Material

PHR3221

Phenylephrine Bitartrate, pharmaceutical secondary standard, certified reference material

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

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A G Tahiliani et al.
General pharmacology, 13(5), 369-374 (1982-01-01)
To summarize, a large number of studies indicate that the effects of phenylephrine on cardiac contractility are mediated through alpha-adrenoceptors, although not exclusively. There are an equally large number of reports indicating some beta-adrenoceptor stimulant effects of phenylephrine. Of the
Ashraf S Habib
Anesthesia and analgesia, 114(2), 377-390 (2011-11-23)
Phenylephrine is effective for the management of spinal anesthesia-induced hypotension in parturients undergoing cesarean delivery under spinal anesthesia. While ephedrine was previously considered the vasopressor of choice in obstetric patients, phenylephrine is increasingly being used. This is largely due to
Hartley C Atkinson et al.
European journal of clinical pharmacology, 71(2), 151-158 (2014-12-06)
Over-the-counter combinations containing acetaminophen and phenylephrine for treatment of the common cold and influenza are widespread, but there are few data about pharmacokinetics of these two drugs used in combination. We aimed to investigate pharmacokinetic interactions between acetaminophen and phenylephrine.
Uwe Kirchhefer et al.
The Journal of biological chemistry, 289(1), 163-176 (2013-11-15)
Protein phosphatase 2A (PP2A) is a family of multifunctional serine/threonine phosphatases consisting of a catalytic C, a structural A, and a regulatory B subunit. The substrate and therefore the functional specificity of PP2A are determined by the assembly of the
Joseph R H Mauban et al.
American journal of physiology. Heart and circulatory physiology, 307(2), H173-H181 (2014-05-27)
We used two-photon (2-p) Förster resonance energy transfer (FRET) microscopy to provide serial, noninvasive measurements of [Ca(2+)] in arterioles of living "biosensor" mice. These express a genetically encoded Ca(2+) indicator (GECI), either FRET-based exMLCK or intensity-based GCaMP2. The FRET ratios
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