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G0700000

Guaifenesin

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

Guaiacol glyceryl ether, 3-(o-Methoxyphenoxy)-1,2-propanediol, Glycerol guaiacolate, Guaifenesin

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About This Item

Fórmula empírica (notación de Hill):
C10H14O4
Número de CAS:
93-14-1
Peso molecular:
198.22
Número MDL:
MFCD00016873
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329799714
NACRES:
NA.24

grado

pharmaceutical primary standard

familia API

guaifenesin

fabricante / nombre comercial

EDQM

aplicaciones

pharmaceutical (small molecule)

Formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

COc1ccccc1OCC(O)CO

InChI

1S/C10H14O4/c1-13-9-4-2-3-5-10(9)14-7-8(12)6-11/h2-5,8,11-12H,6-7H2,1H3

Clave InChI

HSRJKNPTNIJEKV-UHFFFAOYSA-N

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Guaifenesin EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

Producto relacionado

Referencia del producto
Descripción
Precios

1301007

Guaifenesin, United States Pharmacopeia (USP) Reference Standard

79213

1,1′-Oxybis[3-(2-methoxyphenoxy)-2-propanol], pharmaceutical impurity standard

PHR1543

Guaifenesin Impurity B, Pharmaceutical Secondary Standard; Certified Reference Material

Y0001956

Guaifenesin for peak identification, European Pharmacopoeia (EP) Reference Standard

PHR2326

Guaifenesin Impurity D, Pharmaceutical Secondary Standard; Certified Reference Material

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Guaifenesin Impurity C, certified reference material, pharmaceutical secondary standard

1349149

Isoguaifenesin, United States Pharmacopeia (USP) Reference Standard

Pictogramas

Exclamation mark
GHS07

Palabra de señalización

Warning

Frases de peligro

H302

Consejos de prudencia

P301 + P312 + P330

Clasificaciones de peligro

Acute Tox. 4 Oral

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

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Sigma-Aldrich

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William Storms et al.
Current allergy and asthma reports, 9(2), 101-106 (2009-02-13)
Mucus in the airways is a complex mixture of water, lipids, glycoproteins, sugars, and electrolytes that serves as a lubricant for the epithelium. The efficient flow of respiratory mucus is a first level of immune defense that requires an appropriate
Stephen Bennett et al.
Journal of alternative and complementary medicine (New York, N.Y.), 10(6), 967-969 (2005-01-28)
Ephedrine and guaifenesin are herbal supplements that have experienced increased use over the past decade. Ephedrine has been used as a stimulant and weight-loss product, guaifenesin as an expectorant and cough suppressant; both are found in combination in many antitussives
Robert R Fayzullin et al.
Journal of pharmaceutical sciences, 103(10), 3176-3182 (2014-08-06)
The solubility of 3-(2-methoxyphenoxy)-propane-1,2-diol, the well-known chiral drug guaifenesin 1, in water has been investigated by means of polythermal and isothermal approaches. It was found that the solubilities of racemic and enantiomeric diols rac- and (R)-1 depend strongly on temperature.
Clinical inquiries. Is guaifenesin safe during pregnancy?
Roberto Silva et al.
The Journal of family practice, 56(8), 669-670 (2007-08-03)
Question: does guaifenesin improve outcomes in patients with cough associated with upper respiratory infection compared with no intervention?
Nesser Ramirez et al.
The Journal of the Oklahoma State Medical Association, 105(10), 397-398 (2013-01-16)
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