524394

4α-Phorbol-12,13-didecanoate

>99% (HPLC), solid, PDD and PMA negative control, Calbiochem^®

• Sinónimos: 4α-Phorbol-12,13-didecanoate, 4αPDD, PKC Activator I, Negative Control
• Fórmula empírica (notación de Hill): C₄₀H₆₄O₈
• Número de CAS: 27536-56-7
• Peso molecular: 672.93
• Número MDL: MFCD00036737
• Código UNSPSC: 12352211
• NACRES: NA.77

Propiedades

• Nombre del producto: 4α-Phorbol-12,13-didecanoate, Inactive on mouse skin as an inflammatory and tumor-promoting agent.
• Nivel de calidad: 100
• Ensayo: >99% (HPLC)
• Formulario: solid
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze
• solubilidad: DMSO: soluble; ethanol: soluble
• Condiciones de envío: ambient
• temp. de almacenamiento: −20°C
• cadena SMILES: O([C@]21[C@H]([C@H]3[C@@]([C@H]4[C@@](CC(=C3)CO)(C(=O)C(=C4)C)O)([C@@H]([C@H]2OC(=O)CCCCCCCCC)C)O)C1(C)C)C(=O)CCCCCCCCC
• InChI: 1S/C40H64O8/c1-7-9-11-13-15-17-19-21-32(42)47-36-28(4)39(46)30(24-29(26-41)25-38(45)31(39)23-27(3)35(38)44)34-37(5,6)40(34,36)48-33(43)22-20-18-16-14-12-10-8-2/h23-24,28,30-31,34,36,41,45-46H,7-22,25-26H2,1-6H3/t28-,30+,31-,34-,36-,38+,39-,40-/m1/s1
• Clave InChI: DGOSGFYDFDYMCW-OEFRVDPMSA-N

Descripción

Descripción general

Inactive on mouse skin as an inflammatory and tumor-promoting agent. Useful as a negative control for Phorbol-12,13-didecanoate (PDD; Cat. No. 524392) and Phorbol-12-myristate-13-acetate (PMA; Cat. No. 524400).

Reported to be inactive on mouse skin as an inflammatory and tumor-promoting agent. Used as a negative control for phorbol-12,13-didecanoate (PDD, Cat. No. 524392) and phorbol-12-myristate-13-acetate (PMA, Cat. No. 524400).

Acciones bioquímicas o fisiológicas

Cell permeable: no

Primary Target
A negative control for Phorbol-12,13-didecanoate (PDD) and Phorbol-12-myristate-13-acetate (PMA)

Product does not compete with ATP.

Reversible: no

Envase

Packaged under inert gas

Advertencia

Toxicity: Highly Toxic (H)

Reconstitución

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 6 months at -20°C.

Otras notas

Akiguchi, I., et al. 1993. Endocrinology 138, 379.
Clarke, B.L., et al. 1993. Endocrinology132, 1168.
Natarajan, V. and Garcia, J.G. 1993. J. Lab. Clin. Med.121, 337.
Slomiany, B.L., et al. 1992. J. Physiol. Pharmacol.43, 223.

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Pictogramas: GHS06,GHS08,GHS05
• Palabra de señalización: Danger
• Frases de peligro: H300 + H310 + H330,H314,H317,H334,H351
• Consejos de prudencia: P201 - P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Clasificaciones de peligro: Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 2 Oral - Carc. 2 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1
• Código de clase de almacenamiento: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable