Saltar al contenido
Merck
Todas las fotos(2)

Documentos

06-709

Sigma-Aldrich

Anti-Gq/11α Antibody, CT

Upstate®, from rabbit

Sinónimos:

Anti-FBH, Anti-FHH2, Anti-GNA-11, Anti-HG1K, Anti-HHC2, Anti-HYPOC2

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización


About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, mouse

manufacturer/tradename

Upstate®

technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... GNA11(2767)
mouse ... Gna11(14672)

Categorías relacionadas

Specificity

Gqα and G11α

Immunogen

peptide (QLNLKEYNLV) corresponding to amino acids 350-359 of Gqα or G11α

Application

Research Category
Signaling
Research Sub Category
GPCR, cAMP/cGMP & Calcium Signaling
This Anti-Gq/11α Antibody, CT is validated for use in IP, WB for the detection of Gq/11α.

Quality

routinely evaluated by immunoblot on rat brain microsomal preparation

Target description

42kDa

Physical form

Format: Purified
PBS, pH 7.4
Protein A chromatography

Storage and Stability

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

¿No encuentra el producto adecuado?  

Pruebe nuestro Herramienta de selección de productos.

Optional

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Justyna Róg et al.
Biochimica et biophysica acta. Molecular basis of disease, 1865(6), 1138-1151 (2019-01-27)
Pathophysiology of Duchenne Muscular Dystrophy (DMD) is still elusive. Although progressive wasting of muscle fibres is a cause of muscle deterioration, there is a growing body of evidence that the triggering effects of DMD mutation are present at the earlier
4-Hydroxynonenal, an aldehydic product of lipid peroxidation, impairs signal transduction associated with muscarinic acetylcholine and metabotropic glutamate receptors: possible action on G alpha(q/11).
Blanc, E M, et al.
Journal of Neurochemistry, 69, 570-580 (1997)
Margarida Ressurreição et al.
Scientific reports, 6, 35614-35614 (2016-10-21)
During infection of their human definitive host, schistosomes transform rapidly from free-swimming infective cercariae in freshwater to endoparasitic schistosomules. The 'somules' next migrate within the skin to access the vasculature and are surrounded by host molecules that might activate intracellular
Jérôme Lannes et al.
Scientific reports, 6, 31563-31563 (2016-08-20)
The GnRH neurohormone is the main activator of the pituitary gonadotropins, LH and FSH. Here we investigated the contribution of microRNAs in mediating GnRH activation. We first established that miR-125b targets several actors of Gαq/11 signalling pathway, without altering Gαs
Cesar Adolfo Sánchez Triviño et al.
Frontiers in cellular neuroscience, 16, 838939-838939 (2022-03-05)
Although lithium has long been one of the most widely used pharmacological agents in psychiatry, its mechanisms of action at the cellular and molecular levels remain poorly understood. One of the targets of Li+ is the phosphoinositide pathway, but whereas

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico