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H58005

Sigma-Aldrich

4-Quinolinol

98%

Sinónimos:

4-Hydroxyquinoline

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About This Item

Fórmula empírica (notación de Hill):
C9H7NO
Número de CAS:
611-36-9
Peso molecular:
145.16
Beilstein/REAXYS Number:
2900
EC Number:
210-268-2
MDL number:
MFCD00006777
UNSPSC Code:
12352100
PubChem Substance ID:
24895711
NACRES:
NA.22

assay

98%

mp

200-202 °C (lit.)

SMILES string

Oc1ccnc2ccccc12

InChI

1S/C9H7NO/c11-9-5-6-10-8-4-2-1-3-7(8)9/h1-6H,(H,10,11)

InChI key

PMZDQRJGMBOQBF-UHFFFAOYSA-N

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General description

4-Quinolinol (4-quinolone) is a quinolone compound which forms the core moiety of antibacterials such as norfloxacin, nalidixic acid, ciprofloxacin and cinoxacin.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Josip Podobnik et al.
Biomolecules, 10(11) (2020-11-19)
Juvenile delinquency is related to several biological factors, yet very few vulnerability biomarkers have been identified. Previous data suggest that the enzyme monoamine oxidase B (MAO-B) influences several personality traits linked to the propensity to engage in delinquent behavior. Building
Óscar M Bautista-Aguilera et al.
International journal of molecular sciences, 21(11) (2020-06-04)
In this communication, we report the synthesis and cholinesterase (ChE)/monoamine oxidase (MAO) inhibition of 19 quinolinones (QN1-19) and 13 dihydroquinolinones (DQN1-13) designed as potential multitarget small molecules (MSM) for Alzheimer's disease therapy. Contrary to our expectations, none of them showed
Takeshi Fuchigami et al.
Nuclear medicine and biology, 35(2), 203-212 (2008-03-04)
High-affinity iodine- and ethyl-C-5 substituted analogs of 4-hydroxy-3-(3-[11C]methoxyphenyl)-2(1H)-quinolone ([11C]4HQ) were synthesized as new positron emission tomography radioligands for the glycine-binding sites of the N-methyl-d-aspartate (NMDA) ion channel. Although both radioligands showed high in vitro specific binding to rat brain slices
Roman Kimmel et al.
Carbohydrate research, 345(6), 768-779 (2010-03-09)
A comparative study for selective glucosylation of N-unsubstituted 4-hydroxyquinolin-2(1H)-ones into 4-(tetra-O-acetyl-beta-D-glucopyranosyloxy)quinolin-2(1H)-ones is reported. Four glycosyl donors including tetra-O-acetyl-alpha-D-glucopyranosyl bromide, beta-D-glucose pentaacetate, glucose tetraacetate and tetra-O-acetyl-alpha-D-glucopyranosyl trichloroacetimidate were tested, along with different promoters and reaction conditions. The best results were obtained
G C Ragos et al.
Farmaco (Societa chimica italiana : 1989), 53(8-9), 611-616 (1999-03-19)
A new sensitive, rapid and accurate spectrofluorimetric method, suitable for the determination of micromolar concentrations of iron(III) in bovine liver, using 4-hydroxyquinoline (4-HQ) in an alkaline medium (KOH 2.0 x 10(-2) mol/l) as fluorescent agent, is described. The fluorescence intensity
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