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530409

Sigma-Aldrich

Propargyl bromide solution

80 wt. % in xylene

Sinónimos:

3-Bromo-1-propyne

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About This Item

Fórmula lineal:
HC≡CCH2Br
Número de CAS:
106-96-7
Peso molecular:
118.96
Beilstein/REAXYS Number:
605309
MDL number:
MFCD00000241
UNSPSC Code:
12352100
PubChem Substance ID:
24877746
NACRES:
NA.22

concentration

80 wt. % in xylene

refractive index

n20/D 1.494

bp

97 °C

density

1.34 g/mL at 25 °C

storage temp.

2-8°C

SMILES string

BrCC#C

InChI

1S/C3H3Br/c1-2-3-4/h1H,3H2

InChI key

YORCIIVHUBAYBQ-UHFFFAOYSA-N

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General description

The product is an 80wt.% solution of propargyl bromide (3-bromo-1-propyne) in xylene.

Application

Propargyl bromide solution (80wt.% solution in xylene) may be used in the preparation of dimethyl 5-hydroxyisophthalate propargyl ether.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Asp. Tox. 1 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT RE 2 Inhalation - STOT SE 3

target_organs

Central nervous system,Liver,Kidney, Respiratory system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

45.0 °F - closed cup

flash_point_c

7.22 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Self-assembly of amphiphilic polymeric dendrimers synthesized with selective degradable linkages.
Urbani CN, et al.
Macromolecules, 41(1), 76-86 (2008)
Francesco Alessandrini et al.
International immunopharmacology, 29(1), 105-109 (2015-06-03)
The involvement of muscarinic receptors in cancer has been reported. Recently we have demonstrated that the activation of M2 muscarinic receptors, through arecaidine propargyl ester, arrests cell proliferation and induces apoptosis in primary and established glioblastoma cell lines. Considering the
Maria Di Bari et al.
Neurochemistry international, 90, 261-270 (2015-10-13)
Glioblastomas are the most common brain tumors in humans. Previously, we demonstrated that the muscarinic receptor agonist, arecaidine propargyl ester, via M2 receptors, inhibits cell proliferation in a time and dose-dependent manner and induces a severe apoptosis in human U251
Jong Hwan Kwak et al.
Biomaterials, 61, 52-60 (2015-05-23)
We studied the blood-brain barrier (BBB) permeability and intracellular localization of a fluorescein isothiocyanate (FITC)-labeled dieckol (1) and a rhodamine B-labeled dieckol (7), for exploring the possible therapeutic application of fluorone-labeled dieckols in neurodegenerative diseases. Both compounds (1 &7) were
Abdelaziz Al Ouahabi et al.
Journal of the American Chemical Society, 137(16), 5629-5635 (2015-04-09)
Sequence-defined non-natural polyphosphates were prepared using iterative phosphoramidite protocols on a polystyrene solid support. Three monomers were used in this work: 2-cyanoethyl (3-dimethoxytrityloxy-propyl) diisopropylphosphoramidite (0), 2-cyanoethyl (3-dimethoxytrityloxy-2,2-dimethyl-propyl) diisopropylphosphoramidite (1), and 2-cyanoethyl (3-dimethoxytrityloxy-2,2-dipropargyl-propyl) diisopropylphosphoramidite (1'). Phosphoramidite coupling steps allowed rapid synthesis

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