159034

Acetohydroxamic acid

98%

• Sinónimos: AHA
• Fórmula lineal: CH₃CONHOH
• Número de CAS: 546-88-3
• Peso molecular: 75.07
• Beilstein/REAXYS Number: 1739019
• EC Number: 208-913-8
• MDL number: MFCD00009994
• UNSPSC Code: 12352100
• PubChem Substance ID: 24849786
• NACRES: NA.22

Propiedades

• assay: 98%
• mp: 88-90 °C (lit.)
• SMILES string: CC(NO)=O
• InChI: 1S/C2H5NO2/c1-2(4)3-5/h5H,1H3,(H,3,4)
• InChI key: RRUDCFGSUDOHDG-UHFFFAOYSA-N
• Gene Information: human ... CA2(760) , MMP3(4314)

Descripción

General description

Acetohydroxamic acid is a potent inhibitor of bacterial urease activity and reduces urinary ammonia levels. 2-Acetohydroxamic acid loaded floating microspheres forms an efficient drug delivery system for the treatment of Helicobacter pylori.

Application

Acetohydroxamic acid was used:

• to study the mechanism of complexation of iron (III) with acetohydroxamic acid
• to study the inhibitory mechanism of lansoprazole and omeprazole on Helicobacter pyloni
• in urease inhibition studies
• for in situ generation of nitrosocarbonylmethane as a Diels-Alder dienophile

Used in urease inhibition studies and for in situ generation of nitrosocarbonylmethane as a Diels-Alder dienophile.

Información de seguridad

• pictograms: GHS08
• signalword: Danger
• hcodes: H360
• pcodes: P201 - P308 + P313
• Hazard Classifications: Repr. 1B
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• ppe: Eyeshields, Gloves, type P2 (EN 143) respirator cartridges