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14501

Sigma-Aldrich

Poly(ethylene glycol) bis(amine)

Mw 2,000, carboxyl reactive, amine

Sinónimos:

Polyethylene glycol, O,O′-Bis(2-aminoethyl)polyethylene glycol, Diaminopolyethylene glycol, PEG-diamine, Polyoxyethylene bis(amine)

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About This Item

Fórmula lineal:
H2N(CH2CH2O)nCH2CH2NH2
Número de CAS:
24991-53-5
MDL number:
MFCD00132004
UNSPSC Code:
12162002
PubChem Substance ID:
24848541
NACRES:
NA.23

product name

Poly(ethylene glycol) bis(amine), Mw 2,000

form

powder

Quality Level

100

mol wt

Mw 2,000

reaction suitability

reagent type: cross-linking reagent
reactivity: carboxyl reactive

Ω-end

amine

α-end

amine

polymer architecture

shape: linear
functionality: homobifunctional

storage temp.

−20°C

InChI

1S/C6H16N2O2/c7-1-3-9-5-6-10-4-2-8/h1-8H2

InChI key

IWBOPFCKHIJFMS-UHFFFAOYSA-N

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Categorías relacionadas

Application


  • Polyethylene Glycol Conjugated Polymeric Nanocapsules for Targeted Delivery of Quercetin to Folate-Expressing Cancer Cells in Vitro and in Vivo: Discusses the use of PEG-bis amine for creating polymeric nanocapsules aimed at enhancing targeted drug delivery (RI El-Gogary et al., 2014).

Other Notes

Polymer for preparing enzyme conjugates soluble in organic solvents; Promising drug carrier

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

Certificados de análisis (COA)

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L Kelemen et al.
Lab on a chip, 19(11), 1985-1990 (2019-05-03)
Whispering gallery mode (WGM) resonators are promising optical structures for microfluidic label-free biosensors mainly due to their high sensitivity, but from a practical point of view they present numerous constraints that make their use in real laboratory diagnosis application difficult.
Urrotigoity, M. and Souppe, J.
Biocatalysis, 2, 145-145 (1989)
K Kawasaki et al.
Chemical & pharmaceutical bulletin, 43(12), 2133-2138 (1995-12-01)
Hybrids of fibronectin-related peptides [Arg-Gly-Asp (RGD), Arg-Gly-Asp-Ser (RGDS)] and poly(ethylene glycol) (PEG) were prepared and their inhibitory effects on experimental metastasis in mice were examined. The inhibitory effect of RGD was markedly potentiated by hybrid formation with poly(ethylene glycol) #6000.
N P Desai et al.
Journal of microencapsulation, 17(6), 677-690 (2000-11-04)
A mixture of alginate and polyethylene glycol acrylate was investigated as a system for the encapsulation of islets of Langerhans. This system showed dual crosslinkability: the alginate was ionically crosslinked by multivalent cations, and the PEG was covalently crosslinked by
Joseph Deere et al.
Langmuir : the ACS journal of surfaces and colloids, 24(20), 11762-11769 (2008-09-27)
The use of alpha-chymotrypsin to cleave covalently bound N-acetyl- l-tryptophan (Ac-Trp-OH) from the surfaces of aminopropylated controlled pore glass (CPG) and the polymer PEGA 1,900 was investigated. Oligoglycine spacer chains were used to present the covalently attached Ac-Trp-OH substrate to
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Artículos

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Versatile Cell Culture Scaffolds: Bio-orthogonal Click

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

Versatile Cell Culture Scaffolds: Bio-orthogonal Click

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

Versatile Cell Culture Scaffolds: Bio-orthogonal Click

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

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