Skip to Content
Merck
  • Scandium triflate catalyzed cycloaddition of imines with 1,1-cyclopropanediesters: efficient and diastereoselective synthesis of multi-substituted pyrrolidines.

Scandium triflate catalyzed cycloaddition of imines with 1,1-cyclopropanediesters: efficient and diastereoselective synthesis of multi-substituted pyrrolidines.

Organic & biomolecular chemistry (2006-01-05)
Yan-Biao Kang, Yong Tang, Xiu-Li Sun
ABSTRACT

A tandem ring-opening-cyclization reaction of cyclopropanes with imines in the presence of 5 mol% of scandium triflate was developed for the highly diastereoselective synthesis of multi-substituted pyrrolidines.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Cyclopropane-1,1-dicarboxylic acid, 97%