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Key Documents

SMB00902

Sigma-Aldrich

Z-Lycopene

Balanced with Lycopene

Synonym(s):

Poly-cis-lycopene, cis-Lycopene

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About This Item

Empirical Formula (Hill Notation):
C40H56
Molecular Weight:
536.87
UNSPSC Code:
12352205
NACRES:
NA.28

biological source

plant

form

powder

mol wt

536.87

composition

Lycopene, ≤40% HPLC
Z-Lycopene, ≥60% HPLC

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

shipped in

dry ice

storage temp.

−70°C

General description

Z-Lycopene, also known as cis-lycopene, is a carotenoid and a bioactive natural compound primarily found in Solanum lycopersicum (tomato) along with many fruits and vegetables. Current research indicates that this metabolite is an inhibitor and may possess diverse biological activities, including anticancer, antioxidant, and neuroprotective properties.

Application

Z-Lycopene is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Biochem/physiol Actions

Z-Lycopene is naturally found in small quantities in several types of tomatoes and in higher amounts in processed food (such as: tomato sauce and tomato soup). Furthermore, it was found that Z-Lycopene has higher antioxidant properties than Lycopene (all trans- Lycopene).
In raw food and processed food there are a wide variety of Z-Lycopene isomers, which differ in the geometrical configuration of the molecule. However, the most abundant isomer is the 5Z-Lycopene. Moreover, it was found that consumed Lycopene isomerizes to Z-Lycopene in the body, possibly in the enterocytes while the predominant isomer is the 5Z-Lycopene.

Features and Benefits

  • Suitable for Biochemical and Biomedical research
  • Versatile and adaptable for wide variety of laboratory and research applications

Caution

Light and air sensitive.

Other Notes

For additional information on our range of Biochemicals, please complete this form.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Lycopene isomerisation takes place within enterocytes during absorption in human subjects.
Richelle, M., Sanchez, B., Tavazzi, I., Lambelet, P., Bortlik, K., & Williamson, G.
The British Journal of Nutrition, 103, 1800-1807 (2010)
Comparative study on antioxidant activity of lycopene (Z)-isomers in different assays.
Mu?ller, L., Goupy, P., Fro?hlich, K., Dangles, O., Caris-Veyrat, C., & Bo?hm, V.
Journal of Agricultural and Food Chemistry, 59, 4504-4511 (2011)
The E/Z isomer ratio of lycopene in foods and effect of heating with edible oils and fats on isomerization of (all-E)-lycopene.
Honda, M., Murakami, K., Watanabe, Y., Higashiura, T., Fukaya, T., Kanda, H., & Goto, M.
European Journal of Lipid Science and Technology, 119 (2017)
The thermal Z-isomerization-induced change in solubility and physical properties of (all-E)-lycopene.
Murakami, K., Honda, M., Takemura, R., Fukaya, T., Kubota, M., Kanda, H., & Goto, M.
Biochemical and Biophysical Research Communications, 491, 317-322 (2017)
The proportion of lycopene isomers in human plasma is modulated by lycopene isomer profile in the meal but not by lycopene preparation.
Richelle, M., Lambelet, P., Rytz, A., Tavazzi, I., Mermoud, A. F., Juhel, C.,...& Bortlik, K.
The British Journal of Nutrition, 107, 1482-1488 (2012)

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