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  • [Experimental study on using diclofenac sodium or dionine topically to treat fibrinous membrane after intraocular lens implantation].

[Experimental study on using diclofenac sodium or dionine topically to treat fibrinous membrane after intraocular lens implantation].

Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University (2003-01-23)
S B Jia, L S Tang
RÉSUMÉ

To find a reasonable method for treating and preventing fibrinous membrane after intraocular lens (IOL) implantation by using diclofenac sodium or dionine topically. Forty-eight eyes of twenty-four adult pure bred New Zealand rabbits were divided into three groups randomly. Group A: rabits received diclofenac sodium eyedrops; Group B: rabbits received dionine eyedrops; Group C: controlled. All the eyes received lens extraction combined with posterior chamber intraocular lens implantation. The fibrinous membrane was observed after 1, 3, 5, 7, 14, 21 and 30 days postoperatively. The fibrinous membran in Group A was less than that of Group B and Group C, (P < 0.05); the difference between group B and group C on fibrinous membrance was also statistically significant (P < 0.05). The study suggests that both diclofenac sodium and the dionine eyedrops can treat fibrinous membrane after IOL implantation. The effect of diclofenac sodium is better than that of dionine.