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Merck

Nanoparticles of conjugated polymers prepared from phase-separated films of phospholipids and polymers for biomedical applications.

Advanced materials (Deerfield Beach, Fla.) (2014-05-03)
Jungju Yoon, Jungheon Kwag, Tae Joo Shin, Joonhyuck Park, Yong Man Lee, Yebin Lee, Jonghyup Park, Jung Heo, Chulmin Joo, Tae Jung Park, Pil J Yoo, Sungjee Kim, Juhyun Park
RÉSUMÉ

Phase separation in films of phospholipids and conjugated polymers results in nanoassemblies because of a difference in the physicochemical properties between the hydrophobic polymers and the polar lipid heads, together with the comparable polymer side-chain lengths to lipid tail lengths, thus producing nanoparticles of conjugated polymers upon disassembly in aqueous media by the penetration of water into polar regions of the lipid heads.

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Avanti
08:0 PE, 1,2-dioctanoyl-sn-glycero-3-phosphoethanolamine, powder