58221-U
SUPELCOSIL™ LC-CN (5 µm) HPLC Columns
L × I.D. 15 cm × 4.6 mm, HPLC Column
Synonyme(s) :
COLONNE HPLC MTO-SUPELCOSIL™ LC-CN 3UM 15CMX4.6MM
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About This Item
Code UNSPSC :
41115700
eCl@ss :
32110501
Nomenclature NACRES :
SB.52
Produits recommandés
product name
Colonne HPLC SUPELCOSIL™ LC-CN, 5 μm particle size, L × I.D. 15 cm × 4.6 mm
Matériaux
stainless steel column
Niveau de qualité
Agence
suitable for USP L10
Gamme de produits
SUPELCOSIL™
Caractéristiques
endcapped
Conditionnement
1 ea of
Ampleur du marquage
4% Carbon loading
Paramètres
≤70 °C temp. range
Technique(s)
HPLC: suitable
L × D.I.
15 cm × 4.6 mm
Superficie
170 m2/g
Couverture de surface
surface coverage 3.5 μmol/m2
Matrice
silica gel, spherical particle platform
fully porous particle
Groupe de la matrice active
cyano phase
Taille des particules
5 μm
Dimension de pores
120 Å
Plage de pH
2-7.5
Technique de séparation
hydrophilic interaction (HILIC)
normal phase
reversed phase
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Description générale
La phase LC-CN est souvent utilisée à la place de la silice parce qu′elle offre les avantages d′une phase gréffée (telle qu′une équilibration rapide, et une sensibilité moindre aux faibles variations de concentration en eau de la phase mobile). Plus souvent, néanmoins, les colonnes LC-CN sont utilisées avec des phases mobiles de phase inverse.
Application
- Validated Simple HPLC-UV Method for Mycophenolic Acid (MPA) Monitoring in Human Plasma. Internal Standardization: : This study presents a validated HPLC-UV method for monitoring mycophenolic acid in human plasma. The research highlights the necessity and efficiency of internal standardization in achieving accurate measurements. (Kunicki PK et al., 2021).
- An Improved HPLC Method for Therapeutic Drug Monitoring of Daunorubicin, Idarubicin, Doxorubicin, Epirubicin, and Their 13-dihydro Metabolites in Human Plasma.: This paper describes an enhanced HPLC method for monitoring therapeutic levels of several chemotherapeutic agents and their metabolites in human plasma, improving the accuracy and reliability of drug monitoring. (Fogli S et al., 1999).
- Analysis of Diltiazem and Desacetyldiltiazem in Serum by High-Performance Liquid Chromatography.: This research focuses on an HPLC method for analyzing diltiazem and its primary metabolite in serum, providing a robust tool for clinical pharmacokinetic studies. (Paczkowski D et al., 1995).
- High-Performance Liquid Chromatographic Method for the Determination of Eclanamine and Its N-Desmethyl and N,N-Didesmethyl Metabolites in Urine.: The study details a high-performance liquid chromatographic method for determining eclanamine and its metabolites in urine, crucial for pharmacokinetic and toxicological analysis. (Lakings DB et al., 1988).
Informations légales
SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC
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D Paczkowski et al.
Polish journal of pharmacology, 47(5), 429-434 (1995-09-01)
This paper describes a simple high-performance liquid chromatographic (HPLC) method for the determination of diltiazem and desacetyldiltiazem in human serum. After basic methyl-tert-butyl ether extraction and back-extraction with hydrochloric acid, the drug and its metabolite was injected into a Supelcosil
S Fogli et al.
Therapeutic drug monitoring, 21(3), 367-375 (1999-06-12)
A single high-performance liquid chromatography (HPLC) method, suitable for the analysis of daunorubicin, idarubicin, doxorubicin, epirubicin, and their 13-dihydro metabolites is validated in the present study. Preparation of plasma samples was performed by a first extraction of analytes with a
H Kataoka et al.
Journal of chromatography. B, Biomedical sciences and applications, 731(2), 353-359 (1999-10-08)
The technique of automated in-tube solid-phase microextraction (SPME) coupled with liquid chromatography-electrospray ionization mass spectrometry (LC-ESI-MS) was evaluated for the determination of ranitidine. In-tube SPME is an extraction technique for organic compounds in aqueous samples, in which analytes are extracted
H Kataoka et al.
Journal of analytical toxicology, 24(4), 257-265 (2000-06-29)
A simple and rapid method for the determination of amphetamine, methamphetamine, and their 3,4-methylenedioxy derivatives in urine samples was developed using automated in-tube solid-phase microextraction (SPME) coupled with liquid chromatography-electrospray ionization mass spectrometry (LC-ESI-MS). In-tube SPME is an extraction technique
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