SBR00057

Retapamulin

≥98% (HPLC)

• Formule empirique (notation de Hill): C₃₀H₄₇NO₄S
• Numéro CAS: 224452-66-8
• Poids moléculaire : 517.76
• Numéro MDL: MFCD11045316
• Code UNSPSC : 51284706
• Nomenclature NACRES : NA.76

Propriétés

• Niveau de qualité: 100
• Pureté: ≥98% (HPLC)
• Forme: powder
• Spectre d'activité de l'antibiotique: Gram-positive bacteria
• Mode d’action: protein synthesis | interferes
• Température de stockage: −20°C
• InChI: 1S/C30H47NO4S/c1-7-28(4)16-24(35-25(33)17-36-22-14-20-8-9-21(15-22)31(20)6)29(5)18(2)10-12-30(19(3)27(28)34)13-11-23(32)26(29)30/h7,18-22,24,26-27,34H,1,8-17H2,2-6H3/t18-,19+,20-,21+,22?,24-,26+,27+,28-,29+,30+/m1/s1
• Clé InChI: STZYTFJPGGDRJD-FJJJPKKESA-N

Description

Description générale

Retapamulin (RET) is a semi-synthetic antibiotic ointment, and pleuromutilin derivative compound. The primary structural difference between pleuromutilin and retapamulin is in the C-14 side chain.

Actions biochimiques/physiologiques

Retapamulin is a potent antibacterial agent against Gram-positive bacteria, especially against Staphylococcus aureus and S. pyogenes. It displays synergistic effects against Enterococcus faecalis in combination with streptogramin (MLS). RET initiates ribosomal arrests at the start codon and enables genes to use alternative translational sites in E. coli.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable