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Key Documents

RAB0224

Sigma-Aldrich

Mouse IFN-γ ELISA Kit

for serum, plasma, cell culture supernatant

Synonyme(s) :

IFN-gamma, Interferon gamma

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About This Item

Code UNSPSC :
41116158
Nomenclature NACRES :
NA.32

Espèces réactives

mouse

Conditionnement

kit of 96 wells (12 strips x 8 wells)

Technique(s)

ELISA: suitable
capture ELISA: suitable

Entrée

sample type cell culture supernatant(s)
sample type serum
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 5 pg/mL
standard curve range: 2.74-2000 pg/mL

Méthode de détection

colorimetric

Conditions d'expédition

wet ice

Température de stockage

−20°C

Informations sur le gène

mouse ... Ifng(15978)

Description générale

The Mouse IFN-γ ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of mouse IFN-γ in serum, plasma and cell culture supernatants.

Immunogène

Recombinant Mouse IFN-γ

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Mouse IFN-γ ELISA Kit has been used to measure serum proinflammatory cytokine levels in a renal ischemia/reperfusion injury model.

Actions biochimiques/physiologiques

Interferon γ (IFN-γ) regulates cell differentiation and inflammatory responses. It stimulates the expression of apoptotic mediators. IFN-γ is associated with rheumatoid arthritis (RA). It reduces the differentiation of T helper (Th) 17 cells and osteoclasts. IFN-γ has immunomodulatory and antiviral activity. It is associated with autoimmune pathology. IFN-γ provides protection against tumor development.

Autres remarques

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

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  • RABWASH420X Wash Buffer (Item B)FDS

Pictogrammes

Corrosion

Mention d'avertissement

Warning

Mentions de danger

Conseils de prudence

Classification des risques

Met. Corr. 1

Code de la classe de stockage

8A - Combustible corrosive hazardous materials


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Interferon-gamma: an overview of signals, mechanisms and functions
Schroder K, et al.
Journal of Leukocyte Biology, 75(2), 163-189 (2004)
Interferon-gamma regulates inflammatory cell death by targeting necroptosis in experimental autoimmune arthritis
Lee SH, et al.
Scientific Reports, 7(1), 10133-10133 (2017)
Qianqian Chen et al.
Journal of photochemistry and photobiology. B, Biology, 216, 112152-112152 (2021-02-21)
Emerging evidence suggests that the gut microbiota plays an important role in the pathological progression of Alzheimer's disease (AD). Photobiomodulation (PBM) therapy is believed to have a positive regulatory effect on the imbalance of certain body functions, including inflammation, immunity
Chris P Verschoor et al.
Infection and immunity, 82(11), 4824-4833 (2014-08-27)
Pneumonia caused by Streptococcus pneumoniae is a major cause of death and an economic burden worldwide. S. pneumoniae is an intermittent colonizer of the human upper respiratory tract, and the ability to control asymptomatic colonization determines the likelihood of developing
Stefanie Raab et al.
Journal of immunology (Baltimore, Md. : 1950), 193(8), 4261-4272 (2014-09-14)
The ability of NK cells to mediate Ab-dependent cellular cytotoxicity (ADCC) largely contributes to the clinical success of antitumor Abs, including trastuzumab, which is approved for the treatment of breast cancer with HER2/neu overexpression. Notably, only ∼25% of breast cancer

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