O2375

L-Ornithine monohydrochloride

≥99%

• Synonyme(s) : (S)-2,5-Diaminopentanoic acid monohydrochloride
• Formule empirique (notation de Hill): C₅H₁₂N₂O₂ · HCl
• Numéro CAS: 3184-13-2
• Poids moléculaire : 168.62
• Numéro Beilstein : 3625847
• Numéro CE : 221-678-6
• Numéro MDL: MFCD00064562
• Code UNSPSC : 12352209
• ID de substance PubChem : 24897960
• Nomenclature NACRES : NA.26

Propriétés

• product name: L-Ornithine monohydrochloride, ≥99%
• Niveau de qualité: 200
• Pureté: ≥99%
• Forme: powder
• Impuretés: ammonia and citrulline, essentially free
• Couleur: white
• Application(s): cell analysis
• Chaîne SMILES: Cl.NCCC[C@H](N)C(O)=O
• InChI: 1S/C5H12N2O2.ClH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H/t4-;/m0./s1
• Clé InChI: GGTYBZJRPHEQDG-WCCKRBBISA-N

Description

Application

L-Ornithine monohydrochloride has been used to study the blocking effect of L-ornithine on the transport system that carries L-arginine for the overproduction of nitric oxide during lipopolysaccharide induced endotoxemia in rat model. It has also been used in decarboxylation test of amino acids.

Actions biochimiques/physiologiques

L-Ornithine is a product of arginase degradation and plays an important role in ammonia metabolism via the urea cycle. In mammals, ornithine serves as a precursor for polyamines and proline biosynthesis. Spermine synthesized from ornithine, is an abundant polyamine observed in tumors such as breast carcinomas. Administration of L-ornithine is known to improve subjective index of sleep quality. L-ornithine reduces the cortisol/DHEA-S (dehydroepiandrosterone) ratio, that is associated with stress. In mice, L-ornithine is found to affect the levels of plasma growth hormone, corticosterone and melatonin levels in mice.

Autres remarques

Product of arginine degradation by arginase

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)