F5178

Flavin-Containing Monooxygenase-5, Microsomes human

recombinant, expressed in baculovirus infected insect cells, buffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer)

• Synonyme(s) : FMO-5
• Numéro de classification (Commission des enzymes): 1.14.13.8 (BRENDA, IUBMB)
• Code UNSPSC : 12352204
• Nomenclature NACRES : NA.54

Propriétés

• Produit recombinant: expressed in baculovirus infected insect cells
• Niveau de qualité: 200
• Forme: buffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer)
• Activité spécifique: ≥700 units/mg protein
• Poids mol.: 55-60 kDa
• Conditionnement: vial of 2.5 mg
• Numéro d'accès UniProt: P49326
• Conditions d'expédition: dry ice
• Température de stockage: −70°C
• Informations sur le gène: human ... FMO5(2330)

Description

Application

FMO5 is the only FMO isoform expressed in both adult and fetal human liver.

Actions biochimiques/physiologiques

FMO′s are responsible for catalyzing the oxygenation of a variety of xenobiotic and drug compounds including environmental pollutants and carcinogens, which demonstrate a nucleophilic nitrogen, sulfur, selenium, and phosphorous-containing moiety associated with their respective oxides. These enzymes are classified as Phase I or oxidative drug metabolism enzymes. FMO5 is the only FMO isoform expressed in both adult and fetal human liver.

Définition de l'unité

methyl p-tolyl sulfide oxidase activity: One unit will catalyze the production of 1.0 picomole of methyl p-tolyl sulfoxide.

Forme physique

Solution in 100 mM potassium phosphate buffer, pH 7.4.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)