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Key Documents

C9858

Sigma-Aldrich

Creatine Kinase MM Fraction from human heart

lyophilized powder

Synonyme(s) :

CK-MM Fraction, Human CK MM, Human Creatine Kinase

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About This Item

Numéro MDL:
Code UNSPSC :
12352204
eCl@ss :
32160410
Nomenclature NACRES :
NA.54

Forme

lyophilized powder

Niveau de qualité

Activité spécifique

≥100 units/mg protein

Numéro d'accès UniProt

Température de stockage

−20°C

Informations sur le gène

human ... CKM(1158)

Spécificité

One unit will transfer 1.0 μmole of phosphate from creatine phosphate to ADP per minute at 37 °C (measured at 340 nm as one equimolar amount of NADH produced by coupled reaction).

Application

Creatine kinase MM fraction from human heart has been used in a study to investigate the importance of intraoperative and postoperative cardiac medical therapy in emergency coronary artery bypass grafting for acute myocardial infarction. Creatine kinase MM fraction from human heart has also been used in a study to investigate the circadian dependence of infarct size and left ventricular function after ST slevation myocardial infarction.

Actions biochimiques/physiologiques

May be used as a control or calibrator in monitoring myocardial injury.

Avertissement

All human source materials have tested negative for HIV1, HIV2, HCV antibodies and HbsAg. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infectious.

Définition de l'unité

One unit will transfer one micromole of phosphate from creatine phosphate to ADP per minute at 37 deg C.

Forme physique

Lyophilized powder containing Tris-HCl, EDTA and N-acetyl cysteine.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Akira Sato et al.
Journal of the American College of Cardiology, 59(8), 730-738 (2012-02-22)
This study evaluated the clinical value of myocardial contrast delayed enhancement (DE) with multidetector computed tomography (MDCT) for predicting clinical outcome after acute myocardial infarction (AMI). Although some studies have described the use of MDCT for assessment of myocardial viability
Ronald Reiter et al.
Circulation research, 110(1), 105-110 (2011-11-19)
In rodents, infarct size after ischemia/reperfusion exhibits a circadian dependence on the time of coronary occlusion. It is not known if a similar circadian dependence of infarct size occurs in humans. To determine if humans exhibit a circadian dependence of
Akira Sezai et al.
Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 18(4), 338-346 (2012-05-11)
The results of emergency coronary artery bypass grafting (CABG) for acute myocardial infarction (AMI) are less than satisfactory, and readmission for cardiac events is common. 105 patients underwent emergency CABG for AMI. We examined the long-term results of emergency CABG
Helen Lee et al.
The European journal of neuroscience, 31(8), 1388-1401 (2010-04-14)
Horizontal cells are lateral interneurons that participate in visual processing in the outer retina but the cellular mechanisms underlying transmitter release from these cells are not fully understood. In non-mammalian horizontal cells, GABA release has been shown to occur by

Chromatograms

application for HPLC

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