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A7003

Sigma-Aldrich

Alginic acid from brown algae

powder

Synonyme(s) :

Alginic acid from Macrocystis pyrifera (kelp), Mixed polymer of mannuronic and guluronic acid

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About This Item

Formule linéaire :
(C6H8O6)n
Numéro CAS:
9005-32-7
Numéro CE :
232-680-1
Numéro MDL:
MFCD00081309
Code UNSPSC :
12171500
Nomenclature NACRES :
NA.47
Le tarif et la disponibilité ne sont pas disponibles actuellement.

Forme

powder

Niveau de qualité

200

Technique(s)

titration: suitable

Couleur

white to light yellow

Plage de pH

1.5-3.5

Pf

300 °C

Solubilité

H2O: insoluble, but swells
aqueous base: soluble

Application(s)

diagnostic assay manufacturing
hematology
histology

Température de stockage

room temp

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Catégories apparentées

Description générale

Alginic acid is a high molecular weight linear polymer isolated from seaweed. It is a linear β-1→4-linked polymer of n-mannuronic and L-guluronic acid. It is an acid polysaccharide present in the extracellular matrix of brown algae.[1] It is reported to inhibit the reverse transcriptase activity of HIV.[1] Structural investigation of alginic acid, a marine algal polysaccharide poly-α-L-guluronic acid, has been reported.[2] Anti-inflammatory effect of alginic acid, isolated from the brown algae Sargassum wightii, in type II collagen induced arthritic rats has been reported.[3] Pyrolysis of alginic acid using py-GC/MS over a wide temperature range (200-800°C) and thermogravimetric analysis (TGA) has been reported.[4] It was reported to cause the biocorrosion of thin films of copper on germanium internal reflection elements (IREs).[5]

Application

Alginic acid is suitable reagent used to study the in-vitro and in-vivo mitogenic activity of alginates.[6] It is suitable for use in the spectrophotometric determination of transparent exopolymer particles by dye-binding assay.[7]

Autres remarques

A straight-chain, hydrophilic, colloidal, polyuronic acid composed primarily of anhydro-β-D-mannuronic acid residues with 1→4 linkage.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Certificats d'analyse (COA)

Lot/Batch Number
0000421548
0000421548
0000401399
0000399352
0000382762

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C H Sarithakumari et al.
International immunopharmacology, 17(4), 1108-1115 (2014-01-22)
The present study evaluated the anti-inflammatory potential of alginic acid isolated from the brown algae Sargassum wightii in type II collagen induced arthritic rats, a well established arthritic model that resembles more closely to human rheumatoid arthritis in its clinical
Ramón Rial et al.
Nanomaterials (Basel, Switzerland), 10(7) (2020-07-09)
Hydrogels exhibit excellent properties that enable them as nanostructured scaffolds for soft tissue engineering. However, single-component hydrogels have significant limitations due to the low versatility of the single component. To achieve this goal, we have designed and characterized different multi-component
Structural components of alginic acid. II. The crystalline structure of poly-alpha-L-guluronic acid. Results of x-ray diffraction and polarized infrared studies.
E D Atkins et al.
Biopolymers, 12(8), 1879-1887 (1973-01-01)
Pyrolysis behaviour of the main carbohydrates of brown macro-algae.
Anastasakis K, et al.
Fuel: The Science and Technology of Fuel and Energy, 90(2), 598-607 (2011)
K C S Queiroz et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 62(5), 303-307 (2008-05-06)
Brown algae have two kinds of acid polysaccharides present in the extracellular matrix: sulfated fucan and alginic acid. We have previously isolated and characterized fucans from several species of brown seaweed. The characterized fucans from Dictyotaceae are heterofucans containing mainly
Afficher tous les articles scientifiques apparentés

Questions

1–3 of 3 Questions  

  1. What is the molecular weight of A7003 alginic acid?

    1 answer

    1. The molecular weight of this product is approximately 240 kDa.

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  2. What is the purity of the product?

    1 answer

    1. The purity of this product is not determined.

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  3. What is the M:G ratio for A7003 alginic acid?

    1 answer

    1. The mannuronic and guluronic content of the alginic acid in product A7003 is not a measured. The information stated on the product datasheet - 61% mannuronic acid and 39% guluronic acid - is on the basis of what is reported in the literature. Please see the link below to review the Product Information Sheet:
      https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/376/103/a7003pis.pdf

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