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Key Documents

A1151

Sigma-Aldrich

Anti-Albumin antibody produced in goat

fractionated antiserum, lyophilized

Synonyme(s) :

Albumin Detection Antibody, Anti-Albumin, Goat Anti-Albumin

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About This Item

Numéro MDL:
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.46

Source biologique

goat

Niveau de qualité

Produit recombinant

expressed in goat

Forme d'anticorps

fractionated antiserum

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

lyophilized

Poids mol.

antigen 65 kDa

Espèces réactives

human

Conditionnement

vial of 2 mL lyophilized antiserum

Technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable

Numéro d'accès UniProt

Température de stockage

2-8°C

Informations sur le gène

human ... ALB(213)

Description générale

Albumin, the major protein produced by liver cells, represents more than half of the total protein content of human serum. Many other body fluids also contain albumin. Three major functions for serum albumin have been proposed: maintenance of osmotic pressure, transportation of a variety of substances and an endogenous source of amino acids. The primary sites of albumin degradation are not known, but the protein can be metabolized by almost every organ in the body. Determination of serum albumin levels is a widely used screening test in clinical medicine. A decrease in serum albumin levels may indicate disease states such as malnutrition, cirrhosis, nephrotic syndrome, diabetes, gastrointestinal and hepatic diseases, thermal burns and pulmonary disease.
Goat polyclonal anti-Albumin antiserum is immunospecific for human albumin by immunoelectrophoresis against normal human serum and human albumin. Identity and purity of the specific antibody is established by immunoelectrophoresis (IEP). Electrophoresis of the antiserum followed by diffusion against anti-goat serum results in multiple arcs of precipitation, whereas against anti-goat IgG, it results in a single arc of precipitation in the γ region.

Immunogène

purified human albumin

Application

Goat polyclonal anti-Albumin antiserum is used to tag albumin for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of albumin a variety of clinical indications.

Forme physique

Lyophilized from 0.01 M phosphate buffered saline, pH 7.2

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


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Consulter la Bibliothèque de documents

Elliott L Rodriguez et al.
Journal of chromatography. A, 1638, 461683-461683 (2020-11-24)
Diabetes is characterized by elevated levels of blood glucose, which can result in the modification of serum proteins. The modification of a protein by glucose, or glycation, can also lead to the formation of advanced glycated end-products (AGEs). One protein
Ryan Matsuda et al.
Journal of chromatography. A, 1416, 112-120 (2015-09-19)
A method combining on-line immunoextraction microcolumns with high-performance affinity chromatography (HPAC) was developed and tested for use in examining drug-protein interactions with normal or modified proteins. Normal human serum albumin (HSA) and glycated HSA were used as model proteins for
Elliott L Rodriguez et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1136, 121812-121812 (2019-12-17)
An on-line purification and entrapment system was developed that could extract a protein from a sample such as serum and entrap this protein within a small column for use in high-performance affinity chromatography. Human serum albumin (HSA) was employed as
Sadia Sharmeen et al.
Current protocols, 3(8), e867-e867 (2023-08-23)
Immunoaffinity chromatography (IAC) is a type of liquid chromatography that uses immobilized antibodies or related binding agents as selective stationary phases for sample separation or analysis. The strong binding and high selectivity of antibodies have made IAC a popular tool
Guanglong Ma et al.
JCI insight, 9(10) (2024-05-07)
The homeostasis of IgG is maintained by the neonatal Fc receptor, FcRn. Consequently, antagonism of FcRn to reduce endogenous IgG levels is an emerging strategy for treating antibody-mediated autoimmune disorders using either FcRn-specific antibodies or an engineered Fc fragment. For

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