84797

Poly(éthylène glycol)

BioUltra, 2,000

• Synonyme(s) : PEG
• Formule linéaire : H(OCH₂CH₂)_nOH
• Numéro CAS: 25322-68-3
• Numéro MDL: MFCD00081839
• Code UNSPSC : 12352104
• ID de substance PubChem : 24888269
• Nomenclature NACRES : NA.26

Propriétés

• Gamme de produits: BioUltra
• Forme: powder
• Poids mol.: M_r 1900-2200
• Impuretés: insoluble matter:, passes filter test; ≤0.001% peroxides (as H₂O₂):
• pH: 5.5-7.0 (25 °C, 50 mg/mL in H₂O)
• Pf: 50-53 °C
• Solubilité: H₂O: 50 mg/mL at 25 °C, clear, colorless
• Traces d'anions: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• Traces de cations: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤200 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Na: ≤200 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• λ: 50 mg/mL in H₂O
• Absorption UV: λ: 260 nm A_max: ≤0.1; λ: 280 nm A_max: ≤0.04
• Chaîne SMILES: C(CO)O
• InChI: 1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
• Clé InChI: LYCAIKOWRPUZTN-UHFFFAOYSA-N

Description

Description générale

Poly(ethylene glycol) (PEG) is a non-ionic hydrophilic polymer and is available in different molecular weights. It helps in the purification and crystal growth of proteins and nucleic acids. PEG and dextran together result in aqueous polymer two phase system, which is required for the purification of biological materials. PEG also interacts with cell membrane, thereby allowing cell fusion. It exhibitsstealth effect, prolonged blood circulation and excellent biocompatibility. PEG has an ability to elicit hypersensitivity reactions via stimulating complement pathway.

Application

Poly(ethylene glycol) has been used:

• as a constituent in the preparation of liquid desiccant solutions
• as a precipitating agent and additive in protein crystallization
• as a representative biocompatible polymer to decipher its interactions with cellular system at molecular level

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 281.5 °F - closed cup
• Point d'éclair (°C): 138.6 °C - closed cup
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)