Accéder au contenu
Merck
Toutes les photos(1)

Key Documents

View All Documentation

17928

Sigma-Aldrich

O-Methyl-O′-succinylpolyethylene glycol 2′000

Synonyme(s) :

Polyethylene glycol, O-(Succinyl)-O′-methylpolyethylene glycol 2′000, Polyethylene glycol 2′000 monomethyl ether succinate

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
Toutes les photos(1)

About This Item

Formule linéaire :
CH3O(CH2CH2O)nCOCH2CH2COOH
Numéro CAS:
31961-02-1
Numéro MDL:
MFCD00284260
Code UNSPSC :
51171641
Nomenclature NACRES :
NA.26

Forme

powder

Poids mol.

Mr ~2100

Pf

50-53 °C

Extrémité Ω

carboxylic acid

Extrémité α

methoxy

Température de stockage

−20°C

Application

Polyethylene glycol 2000 is used in the construction of biomaterials such as biopolymers, micelles and nanostructures.

Actions biochimiques/physiologiques

O-Methyl-O′-succinylpolyethylene glycol 2′000 is a modified monomethoxypolyethylene glycol (mPEG) wherein the hydroxyl groups are succinylated by succinic anhydride. This succinylated mPEG can then be used to synthesize tolerogenic mPEG conjugates of peptides. Tolerogenic peptide conjugates are very effective reagents for obtaining epitope-specific immunosuppression of antibody responses to immunopathogenic sites on multideterminant complex protein antigens.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Gulam Mustafa Hasan et al.
Journal of parasitology research, 2011, 120462-120462 (2011-07-21)
We have examined the effect of stearylamine (SA) in liposomes on the viability of Plasmodium falciparum in culture by studying the inhibition of incorporation of [(3)H]-hypoxanthine in the nucleic acid of parasites. Stearylamine in liposomes significantly inhibits the growth of
Antitumor effect of liposomal histone deacetylase inhibitor-lipid conjugates in vitro.
Hattori Y, Nagaoka Y, Kubo M, et al.
Chemical & Pharmaceutical Bulletin, 59, 1389-1392 (2011)
Ayman El-Sayed et al.
Journal of pharmaceutical sciences, 101(2), 879-882 (2011-11-17)
We previously reported on a stearylated INF7 peptide (str-INF7), which enhances the endosomal escape of an octaarginine (R8)-modified liposomal particle encapsulating plasmid DNA (pDNA) in a fusion-independent manner. This study examined whether this peptide derivative enhanced the endosomal escape and
Peptide/protein-polymer conjugates: synthetic strategies and design concepts.
Gauthier MA, Klok HA.
Chemical Communications (Cambridge, England), 21, 2591-2611 (2008)
Peter M Fischer et al.
Journal of peptide science : an official publication of the European Peptide Society, 8(9), 529-542 (2002-10-10)
Stepwise synthetic assembly of polypeptide chains reversibly linked to polyethylene glycol represents a hybrid between traditional solution and solid-phase chemistries and combines the inherent advantages of both approaches. The technical simplicity and scalability of the liquid-phase peptide synthesis method renders
Afficher tous les articles scientifiques apparentés

Articles

Magnetic Nanoparticles Synthesis

Prof. Randal Lee discusses iron oxide magnetic nanospheres and nanocubes design considerations for biosensing applications.

Magnetic Nanoparticles Synthesis

Prof. Randal Lee discusses iron oxide magnetic nanospheres and nanocubes design considerations for biosensing applications.

Magnetic Nanoparticles Synthesis

Prof. Randal Lee discusses iron oxide magnetic nanospheres and nanocubes design considerations for biosensing applications.

Magnetic Nanoparticles Synthesis

Prof. Randal Lee discusses iron oxide magnetic nanospheres and nanocubes design considerations for biosensing applications.

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique