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Key Documents

Y0001220

Captopril impurity C

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

(2RS)-2-Methyl-3-sulphanylpropanoic acid, 3-Mercaptoisobutyric acid

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About This Item

Formule empirique (notation de Hill):
C4H8O2S
Numéro CAS:
Poids moléculaire :
120.17
Code UNSPSC :
41116107
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

captopril

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Conditions d'expédition

wet ice

Température de stockage

−20°C

InChI

1S/C4H8O2S.Na/c1-3(2-7)4(5)6;/h3,7H,2H2,1H3,(H,5,6);/q;+1/p-1

Clé InChI

FOTPRJUNQGWLCM-UHFFFAOYSA-M

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Captopril impurity C EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Pictogrammes

Skull and crossbonesCorrosion

Mention d'avertissement

Danger

Mentions de danger

Classification des risques

Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Determination of enantiomeric purity of 3-mercapto-2-methylpropionic acid.
D Wang-Iverson et al.
Journal of chromatography, 408, 365-371 (1987-11-06)
T C Tallant et al.
Journal of bacteriology, 179(22), 6902-6911 (1997-11-26)
During growth on acetate, Methanosarcina barkeri expresses catabolic enzymes for other methanogenic substrates such as monomethylamine. The range of substrates used by cells grown on acetate was further explored, and it was found that cells grown on acetate also converted
Erinn C Howard et al.
Science (New York, N.Y.), 314(5799), 649-652 (2006-10-28)
Flux of dimethylsulfide (DMS) from ocean surface waters is the predominant natural source of sulfur to the atmosphere and influences climate by aerosol formation. Marine bacterioplankton regulate sulfur flux by converting the precursor dimethylsulfoniopropionate (DMSP) either to DMS or to
M R Smith et al.
Bioorganic & medicinal chemistry, 2(7), 589-593 (1994-07-01)
A bacterium (strain photoB) photoassimilated 3-mercapto-2-methylpropionate as sole source of sulphur with methacrylate accumulating in the medium. This was thought to be the product of a sulphur-lyase type enzyme attacking the 3-mercapto-2-methylpropionate. Detailed examination of the biochemistry of the utilization
H G Brittain et al.
Pharmaceutical research, 7(10), 1082-1085 (1990-10-01)
The ultraviolet and circular dichroism spectra of authentic captopril have been obtained, since the reported literature data are inconsistent with those obtained on highly purified material. The UV absorption spectrum consists of a single band maximum at 200 nm, while

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